Abstract：
Artemia is a brine shrimp genus adapted to extreme habitats like ranges salinity from 5-25 g/L and in temperatures from 9 to 35 °C. It is widely distributed and used as an environmental quality biomarker. Artemia franciscana and Artemia salina species are commonly used in ecotoxicological studies and genotoxicity assays due to their short life cycle, high fecundity rate, easy culture, and availability. Thus, considering the importance of these tests in ecotoxicological studies, the present study aimed to present Artemia genus as a biological model in genotoxicity research. To this end, we reviewed the literature, analyzing data published until July 2023 in the Web of Science, SCOPUS, Embase, and PubMed databases. After screening, we selected 34 studies in which the genotoxicity of Artemia for various substances. This review presents the variability of the experimental planning of assays and biomarkers in genotoxicity using Artemia genus as a biological model for ecotoxicological studies and show the possibility of monitoring biochemical alterations and genetic damage effects. Also highlight innovative technologies such as transcriptomic and metabolomic analysis, as well as studies over successive generations to identify changes in DNA and consequently in gene expression.
摘要：
卤虫是一种盐水虾属，适用于极端栖息地，例如盐度范围为5-25g/L，温度为9至35°C。它广泛分布并用作环境质量生物标志物。法国卤虫和盐藻卤虫物种由于其生命周期短，通常用于生态毒理学研究和遗传毒性测定，高繁殖率，简单的文化,和可用性。因此，考虑到这些测试在生态毒理学研究中的重要性，本研究旨在将卤虫属作为遗传毒性研究的生物学模型。为此,我们回顾了文献，分析直到2023年7月在WebofScience上发布的数据，Scopus,Embase,和PubMed数据库。筛选后,我们选择了34项研究，其中卤虫对各种物质具有遗传毒性。这篇综述介绍了使用卤虫属作为生态毒理学研究的生物学模型的遗传毒性测定和生物标志物的实验计划的变异性，并显示了监测生化改变和遗传损伤效应的可能性。还强调创新技术，如转录组学和代谢组学分析，以及连续几代的研究，以确定DNA的变化以及基因表达的变化。
