PDF(Pubmed)
Abstract：
UNASSIGNED: Two-dimensional speckle tracking echocardiography (2D-STE) and three-dimensional echocardiography (3DE) may overcome many limitations of the conventional 2D echocardiography (2DE) in assessing right ventricular (RV) function. We sought to determine whether characteristics of the right atrium and right ventricle as measured by 2D-STE and 3DE are associated with cardiac mortality in patients with ischemic heart failure, over a 6-year follow-up.
UNASSIGNED: The inclusion criteria were ischemic cardiomyopathy with left ventricular ejection fraction of <40% diagnosed using standard 2DE, 2D-STE, and 3DE examination. Patients were followed for 6 years, and cardiac mortality was recorded.
UNASSIGNED: The study sample comprised a total of 54 participants. During the period of follow-up, 24% (13/54) died. The 2DE models showed that being older, having a higher body mass index (BMI), having higher systolic pulmonary artery pressure (SPAP), and a lower RV global longitudinal strain were associated with cardiac mortality in our cohort after 6-year follow-up. Finally, the 3DE models showed that in addition to being older, having higher BMI, having a higher SPAP baseline, lower baseline 3DE RV stroke volume, and larger 3DE RV end-diastolic volume and 3DE RV end-systolic volume were associated with cardiac mortality over 6-year follow-up.
UNASSIGNED: This study provides evidence that RV dysfunction as seen on 2D-STE and 3DE could be associated with increased risk of cardiac-related mortality in patients with heart failure over 6 years.
UNASSIGNED: The inclusion criteria were ischemic cardiomyopathy with left ventricular ejection fraction of <40% diagnosed using standard 2DE, 2D-STE, and 3DE examination. Patients were followed for 6 years, and cardiac mortality was recorded.
UNASSIGNED: The study sample comprised a total of 54 participants. During the period of follow-up, 24% (13/54) died. The 2DE models showed that being older, having a higher body mass index (BMI), having higher systolic pulmonary artery pressure (SPAP), and a lower RV global longitudinal strain were associated with cardiac mortality in our cohort after 6-year follow-up. Finally, the 3DE models showed that in addition to being older, having higher BMI, having a higher SPAP baseline, lower baseline 3DE RV stroke volume, and larger 3DE RV end-diastolic volume and 3DE RV end-systolic volume were associated with cardiac mortality over 6-year follow-up.
UNASSIGNED: This study provides evidence that RV dysfunction as seen on 2D-STE and 3DE could be associated with increased risk of cardiac-related mortality in patients with heart failure over 6 years.
摘要：
■二维斑点追踪超声心动图（2D-STE）和三维超声心动图（3DE）可以克服常规2D超声心动图（2DE）评估右心室（RV）功能的许多局限性。我们试图确定通过2D-STE和3DE测量的右心房和右心室的特征是否与缺血性心力衰竭患者的心脏死亡率相关。为期6年的随访。
■纳入标准为使用标准2DE诊断左心室射血分数<40%的缺血性心肌病，2D-STE,3DE检查。患者随访6年，并记录心脏死亡率.
■研究样本共有54名参与者。在后续行动期间，24%（13/54）死亡。2DE模型显示年龄较大，具有较高的体重指数（BMI），具有较高的收缩期肺动脉压（SPAP），在我们的队列中,6年随访后,较低的RV整体纵向应变与心脏死亡率相关.最后,3DE模型显示，除了年龄较大，有较高的BMI，具有较高的SPAP基线，较低基线3DE右心室每搏输出量，更大的3DERV舒张末期容积和3DERV收缩末期容积与6年随访期间的心脏死亡率相关。
■这项研究提供了证据，证明在2D-STE和3DE上观察到的RV功能障碍可能与6年以上心力衰竭患者的心脏相关死亡风险增加有关。
■纳入标准为使用标准2DE诊断左心室射血分数<40%的缺血性心肌病，2D-STE,3DE检查。患者随访6年，并记录心脏死亡率.
■研究样本共有54名参与者。在后续行动期间，24%（13/54）死亡。2DE模型显示年龄较大，具有较高的体重指数（BMI），具有较高的收缩期肺动脉压（SPAP），在我们的队列中,6年随访后,较低的RV整体纵向应变与心脏死亡率相关.最后,3DE模型显示，除了年龄较大，有较高的BMI，具有较高的SPAP基线，较低基线3DE右心室每搏输出量，更大的3DERV舒张末期容积和3DERV收缩末期容积与6年随访期间的心脏死亡率相关。
■这项研究提供了证据，证明在2D-STE和3DE上观察到的RV功能障碍可能与6年以上心力衰竭患者的心脏相关死亡风险增加有关。
