METHODS: Patients with acute mild to moderate ischemic stroke underwent an overnight HRPO within 48 h of admission. Patients were divided into SDB and no-SDB groups based on oxygen desaturations index(ODI > 10/h). Stepwise multivariate logistic regression analysis was applied to identify the relevant predictors of functional outcome (favorable [mRS 1-2 points] versus unfavorable [mrS > = 3 points]).
RESULTS: Of the 142 consecutively screened patients, 96 were included in the analysis. Of these, 33/96 (34%) were identified as having SDB and were more likely to have unfavorable mRS scores as compared to those without SDB (odds ratio = 2.70, p-value = 0.032).
CONCLUSIONS: HRPO may be a low-cost and easily administered screening method to detect SDB among patients hospitalized for acute ischemic stroke. Patients with SDB (as defined by ODI) have a higher burden of neurological deficits as compared to those without SDB during hospitalization.
方法:急性轻中度缺血性卒中患者在入院后48小时内接受过夜HRPO检查。根据氧去饱和指数(ODI>10/h)将患者分为SDB组和非SDB组。采用逐步多变量逻辑回归分析来确定功能结局的相关预测因素(有利[mRS1-2分]与不利[mrS>=3分])。
结果:在142名连续筛查的患者中,96个被包括在分析中。其中,33/96(34%)被鉴定为具有SDB,与没有SDB的人相比,更可能具有不利的mRS评分(优势比=2.70,p值=0.032)。
结论:HRPO可能是一种低成本且易于使用的筛查方法,可在急性缺血性卒中住院患者中检测SDB。在住院期间,与没有SDB的患者相比,具有SDB(由ODI定义)的患者具有更高的神经缺陷负担。