Abstract：
BACKGROUND: Nickel hypersensitivity is the most common metal related allergy. Nickel containing alloys are frequently used in endovascular devices. The use of intracranial stents in patients with nickel hypersensitivity appears to be safe, but these small series only evaluated arterial stent placement. This case series aimed to assess the safety of intracranial venous stent placement in patients with documented nickel allergy.
METHODS: In this retrospective multicenter case series, patients with idiopathic intracranial hypertension and documented nickel allergy underwent treatment with a permanently implanted nickel containing stent in the dural venous sinuses.
RESULTS: Nine patients with nickel allergy were included. All patients reported clinical improvement in their idiopathic intracranial hypertension symptoms. Of the five patients who had follow-up intracranial venous imaging, all stents remained patent. No patients experienced intraoperative, postoperative, or long term procedure related complications, with follow-up ranging from 1.8 weeks to 49.1 months.
CONCLUSIONS: In this limited case series, the use of nickel containing stents in intracranial venous sinuses in patients with nickel allergy did not result in any allergic reaction or adverse outcome.
METHODS: In this retrospective multicenter case series, patients with idiopathic intracranial hypertension and documented nickel allergy underwent treatment with a permanently implanted nickel containing stent in the dural venous sinuses.
RESULTS: Nine patients with nickel allergy were included. All patients reported clinical improvement in their idiopathic intracranial hypertension symptoms. Of the five patients who had follow-up intracranial venous imaging, all stents remained patent. No patients experienced intraoperative, postoperative, or long term procedure related complications, with follow-up ranging from 1.8 weeks to 49.1 months.
CONCLUSIONS: In this limited case series, the use of nickel containing stents in intracranial venous sinuses in patients with nickel allergy did not result in any allergic reaction or adverse outcome.
摘要：
背景：镍超敏反应是最常见的金属相关过敏。含镍合金经常用于血管内装置中。镍超敏反应患者使用颅内支架似乎是安全的，但这些小系列仅评估动脉支架置入。本病例系列旨在评估有镍过敏记录的患者颅内静脉支架置入的安全性。
方法：在这个回顾性多中心病例系列中，特发性颅内高压和镍过敏的患者接受了在硬脑膜静脉窦永久植入含镍支架的治疗.
结果：包括9例镍过敏患者。所有患者均报告其特发性颅内高压症状的临床改善。在5例接受颅内静脉成像随访的患者中，所有支架仍然是专利。没有患者经历术中，术后,或长期手术相关并发症，随访时间为1.8周至49.1个月。
结论：在此有限病例系列中，镍过敏患者的颅内静脉窦使用含镍支架不会导致任何过敏反应或不良结局.
方法：在这个回顾性多中心病例系列中，特发性颅内高压和镍过敏的患者接受了在硬脑膜静脉窦永久植入含镍支架的治疗.
结果：包括9例镍过敏患者。所有患者均报告其特发性颅内高压症状的临床改善。在5例接受颅内静脉成像随访的患者中，所有支架仍然是专利。没有患者经历术中，术后,或长期手术相关并发症，随访时间为1.8周至49.1个月。
结论：在此有限病例系列中，镍过敏患者的颅内静脉窦使用含镍支架不会导致任何过敏反应或不良结局.
