Abstract：
Oral carcinoma is a common disease that poses challenges in treatment management, especially for advanced cases. Adjuvant therapies, such as radiation and chemoradiation therapy, are typically used for advanced oral cancer patients. However, there is uncertainty regarding the use of adjuvant therapy for early-stage patients with certain soft histological parameters. The UICC manual of clinical oncology suggests that adjuvant therapy for such parameters is desirable but not essential. These parameters include perineural invasion, lymphovascular invasion, single nodal positivity, and patterns of invasion, which complicate the decision-making process for including adjuvant therapy. This review aims to provide evidence-based literature for effectively managing this patient group and developing treatment protocols based on current evidence.
摘要：
口腔癌是一种常见疾病，对治疗管理提出了挑战，特别是对于先进的案例。辅助疗法,如放疗和放化疗,通常用于晚期口腔癌患者。然而,对于具有某些软组织学参数的早期患者使用辅助治疗存在不确定性.临床肿瘤学的UICC手册表明，此类参数的辅助治疗是可取的，但不是必需的。这些参数包括神经周浸润，淋巴管浸润,单节点阳性，和入侵模式，这使得包括辅助治疗的决策过程复杂化。这篇综述旨在提供基于证据的文献，以有效地管理该患者群体并根据当前证据制定治疗方案。
