Abstract：
BACKGROUND: Bipolar disorder (BD) is a chronic pathology that is associated with several impairments throughout a patient\'s life, including decreased sexual function. Despite the importance in quality of life (QoL), functionality and medication adherence, it is still little investigated in these patients.
OBJECTIVE: To compare the sexual function of patients with Bipolar Disorder type I (BD-I), in remission, with healthy controls (HC) and to investigate the clinical and socio-demographic characteristics associated with sexual function in these individuals. Also, to assess the QoL in patients with and without sexual dysfunction (SD).
METHODS: Cross-sectional study with 132 patients with BD-I in euthymic phase and 61 HCs from an outpatient clinic. All the participants were evaluated through the Arizona Sexual Scale (ASEX) and the brief version of the World Health Organization Quality of Life Assessment (WHOQoL-BREF). The patients with BD-I were compared with the HCs. The patients were divided into two groups: the ones diagnosed with SD and the ones without it.
RESULTS: The patients with BD-I had higher rates of SD (42.4%) compared to the HCs (16.4%) (OR 3.67, 95% CI 1.55 - 8.67; p=0.003). SD in patients was associated with being women (p=0.001), older age (p=0.003) and having a longer duration of untreated illness (p=0.010). Patients with SD had worse QoL scores compared to those without SD.
CONCLUSIONS: Patients with BD-I have a high prevalence of SD and this was associated with worse QoL scores in all domains.
OBJECTIVE: To compare the sexual function of patients with Bipolar Disorder type I (BD-I), in remission, with healthy controls (HC) and to investigate the clinical and socio-demographic characteristics associated with sexual function in these individuals. Also, to assess the QoL in patients with and without sexual dysfunction (SD).
METHODS: Cross-sectional study with 132 patients with BD-I in euthymic phase and 61 HCs from an outpatient clinic. All the participants were evaluated through the Arizona Sexual Scale (ASEX) and the brief version of the World Health Organization Quality of Life Assessment (WHOQoL-BREF). The patients with BD-I were compared with the HCs. The patients were divided into two groups: the ones diagnosed with SD and the ones without it.
RESULTS: The patients with BD-I had higher rates of SD (42.4%) compared to the HCs (16.4%) (OR 3.67, 95% CI 1.55 - 8.67; p=0.003). SD in patients was associated with being women (p=0.001), older age (p=0.003) and having a longer duration of untreated illness (p=0.010). Patients with SD had worse QoL scores compared to those without SD.
CONCLUSIONS: Patients with BD-I have a high prevalence of SD and this was associated with worse QoL scores in all domains.
摘要：
背景：双相情感障碍（BD）是一种慢性病理，与患者一生中的多种损伤有关，包括性功能下降。尽管生活质量(QoL)很重要，功能和药物依从性，对这些患者的调查还很少。
目的：比较I型双相情感障碍（BD-I）患者的性功能，在缓解期，与健康对照（HC），并调查与这些个体的性功能相关的临床和社会人口统计学特征。此外，评估有和没有性功能障碍（SD）的患者的QoL。
方法：横断面研究，132例BD-I患者处于正常状态，61例患者来自门诊。通过亚利桑那州性量表（ASEX）和世界卫生组织生活质量评估（WHOQoL-BREF）的简短版本对所有参与者进行了评估。将BD-I患者与HC患者进行比较。患者分为两组：诊断为SD的患者和没有SD的患者。
结果：BD-I患者的SD（42.4％）高于HC（16.4％）（OR3.67，95％CI1.55-8.67；p=0.003）。患者的SD与女性相关（p=0.001），年龄较大（p=0.003），未治疗的疾病持续时间较长（p=0.010）。与没有SD的患者相比，SD患者的QoL评分较差。
结论：BD-I患者的SD患病率较高，这与所有领域的QoL评分较差有关。
目的：比较I型双相情感障碍（BD-I）患者的性功能，在缓解期，与健康对照（HC），并调查与这些个体的性功能相关的临床和社会人口统计学特征。此外，评估有和没有性功能障碍（SD）的患者的QoL。
方法：横断面研究，132例BD-I患者处于正常状态，61例患者来自门诊。通过亚利桑那州性量表（ASEX）和世界卫生组织生活质量评估（WHOQoL-BREF）的简短版本对所有参与者进行了评估。将BD-I患者与HC患者进行比较。患者分为两组：诊断为SD的患者和没有SD的患者。
结果：BD-I患者的SD（42.4％）高于HC（16.4％）（OR3.67，95％CI1.55-8.67；p=0.003）。患者的SD与女性相关（p=0.001），年龄较大（p=0.003），未治疗的疾病持续时间较长（p=0.010）。与没有SD的患者相比，SD患者的QoL评分较差。
结论：BD-I患者的SD患病率较高，这与所有领域的QoL评分较差有关。
