PDF(Pubmed)
Abstract：
BACKGROUND: Sexual dysfunction is the most frequent health problem among psychiatric patients. This could be the result of both the nature of the illness itself and the side effects of prescribed psychotropic medications. It also significantly affects an individual\'s general well-being, interpersonal relationships, self-esteem, and treatment outcomes. Therefore, the current systematic review and meta-analysis was conducted to determine the combined prevalence of sexual dysfunction and its correlated factors among people with mental illness.
METHODS: We retrieved eligible primary studies using various search databases like PubMed, EMBASE, Science Direct, African Journal Online, Google Scholar, and Psychiatry Online. The report of this systematic review was reported following the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. We used standardized data extraction checklists and STATA version 14 for data extraction and analysis, respectively. The I-squared statistics test was used to check statistical heterogeneity within the included articles. Publication bias was assessed using a funnel plot and the Egger test. To estimate the overall prevalence and correlated factors of sexual dysfunction, a random effects model meta-analysis was employed.
RESULTS: In this meta-analysis, a total of 15 primary studies with 2849 psychiatric patients were included. The overall pooled prevalence of sexual dysfunction among psychiatric patients in Africa was 58.42% (95% CI: 49.55, 67.28). Having older age (OR = 1.92, 95% CI: 1.28, 2.87), longer duration of illness (OR = 2.60, 95% CI: 1.14, 5.93), history of relapse (OR = 3.51, 95% CI: 1.47, 8.43), poor quality of life (OR = 3.89, 95% CI: 2.15, 7.05), and antipsychotic medications (OR = 2.99, 95% CI: 1.84, 4.86) were significantly associated with sexual dysfunction.
CONCLUSIONS: This meta-analysis revealed that approximately two-thirds of psychiatric patients in Africa are affected by sexual dysfunction. Therefore, the findings of this study recommend that when evaluating psychiatric patients, health professionals should focus more on sexual dysfunction. It is also essential to promote awareness and incorporate sexual health assessment and intervention into mental health services to reduce the overall burden of the problem.
METHODS: We retrieved eligible primary studies using various search databases like PubMed, EMBASE, Science Direct, African Journal Online, Google Scholar, and Psychiatry Online. The report of this systematic review was reported following the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. We used standardized data extraction checklists and STATA version 14 for data extraction and analysis, respectively. The I-squared statistics test was used to check statistical heterogeneity within the included articles. Publication bias was assessed using a funnel plot and the Egger test. To estimate the overall prevalence and correlated factors of sexual dysfunction, a random effects model meta-analysis was employed.
RESULTS: In this meta-analysis, a total of 15 primary studies with 2849 psychiatric patients were included. The overall pooled prevalence of sexual dysfunction among psychiatric patients in Africa was 58.42% (95% CI: 49.55, 67.28). Having older age (OR = 1.92, 95% CI: 1.28, 2.87), longer duration of illness (OR = 2.60, 95% CI: 1.14, 5.93), history of relapse (OR = 3.51, 95% CI: 1.47, 8.43), poor quality of life (OR = 3.89, 95% CI: 2.15, 7.05), and antipsychotic medications (OR = 2.99, 95% CI: 1.84, 4.86) were significantly associated with sexual dysfunction.
CONCLUSIONS: This meta-analysis revealed that approximately two-thirds of psychiatric patients in Africa are affected by sexual dysfunction. Therefore, the findings of this study recommend that when evaluating psychiatric patients, health professionals should focus more on sexual dysfunction. It is also essential to promote awareness and incorporate sexual health assessment and intervention into mental health services to reduce the overall burden of the problem.
摘要：
背景：性功能障碍是精神病患者中最常见的健康问题。这可能是疾病本身的性质和处方精神药物的副作用的结果。它也会显著影响个人的总体幸福感，人际关系,自尊,和治疗结果。因此,本研究进行了系统评价和荟萃分析,以确定精神疾病患者性功能障碍的综合患病率及其相关因素.
方法：我们使用诸如PubMed、EMBASE,科学直接，非洲在线杂志，谷歌学者，和精神病学在线。本系统评价报告遵循系统评价和荟萃分析（PRISMA）指南的首选报告项目。我们使用标准化的数据提取清单和STATA版本14进行数据提取和分析，分别。I平方统计检验用于检查纳入文章内的统计异质性。使用漏斗图和Egger测试评估出版偏差。估计性功能障碍的总体患病率和相关因素。采用随机效应模型荟萃分析.
结果：在本荟萃分析中，共纳入15项主要研究,共2,849名精神病患者.非洲精神病患者性功能障碍的总体汇总患病率为58.42%(95%CI:49.55,67.28)。年龄较大（OR=1.92，95%CI：1.28，2.87），病程较长（OR=2.60，95%CI：1.14，5.93），复发病史（OR=3.51，95%CI：1.47，8.43），生活质量差(OR=3.89，95%CI：2.15，7.05)，抗精神病药物(OR=2.99,95%CI:1.84,4.86)与性功能障碍显著相关。
结论：这项荟萃分析显示，非洲大约三分之二的精神病患者受到性功能障碍的影响。因此,这项研究的结果表明，在评估精神病患者时，卫生专业人员应该更多地关注性功能障碍。还必须提高认识，并将性健康评估和干预纳入心理健康服务，以减轻问题的总体负担。
方法：我们使用诸如PubMed、EMBASE,科学直接，非洲在线杂志，谷歌学者，和精神病学在线。本系统评价报告遵循系统评价和荟萃分析（PRISMA）指南的首选报告项目。我们使用标准化的数据提取清单和STATA版本14进行数据提取和分析，分别。I平方统计检验用于检查纳入文章内的统计异质性。使用漏斗图和Egger测试评估出版偏差。估计性功能障碍的总体患病率和相关因素。采用随机效应模型荟萃分析.
结果：在本荟萃分析中，共纳入15项主要研究,共2,849名精神病患者.非洲精神病患者性功能障碍的总体汇总患病率为58.42%(95%CI:49.55,67.28)。年龄较大（OR=1.92，95%CI：1.28，2.87），病程较长（OR=2.60，95%CI：1.14，5.93），复发病史（OR=3.51，95%CI：1.47，8.43），生活质量差(OR=3.89，95%CI：2.15，7.05)，抗精神病药物(OR=2.99,95%CI:1.84,4.86)与性功能障碍显著相关。
结论：这项荟萃分析显示，非洲大约三分之二的精神病患者受到性功能障碍的影响。因此,这项研究的结果表明，在评估精神病患者时，卫生专业人员应该更多地关注性功能障碍。还必须提高认识，并将性健康评估和干预纳入心理健康服务，以减轻问题的总体负担。
