Abstract：
The evolution of laser medical devices for benign prostatic hyperplasia (BPH) treatment aims to enhance vaporization, coagulation, or tissue removal. In this study, we aim to evaluate the effectiveness and safety of the innovative application of insulated-gate bipolar transistor (IGBT) xenon lamp-pulsed drive technology holmium laser in endoscopic prostate enucleation operations using canine models. Six canines were used as an experimental unit, the breed of the canine unit used was beagle. Each canine served as its own control to minimize the number of experimental units. Endoscopic enucleation, performed by a single surgeon, involved enucleating the left hemi-prostate, leaving the right hem-prostate untouched to serve as the control. Throughout the study period, all canines maintained good health. No adverse events were observed in all six canines. Postoperatively, there were no indications of redness, swelling, or other adverse effects at the surgical sites. No abnormalities were observed in the appearance and morphology of major organs. The prostate and bladder, removed for further pathological evaluation, exhibited no abnormalities in size, color, or texture. No abnormalities or inflammation were observed, and the tissues were free of adhesions, indicating successful healing. In conclusion, our comparison of preoperative and postoperative parameters in canines suggests that the IGBT pulsed laser, at a power setting of 100 W, demonstrates characteristics of safety, efficacy, minimal tissue damage, and no major postoperative complications. This study establishes a theoretical foundation for future applications in human settings, encouraging further exploration of the IGBT holmium laser\'s potential in clinical practice.
摘要：
用于良性前列腺增生（BPH）治疗的激光医疗设备的发展旨在增强汽化，凝血,或组织切除。在这项研究中,我们的目的是评估绝缘栅双极晶体管(IGBT)氙灯脉冲驱动技术钬激光在犬模型内镜前列腺摘除术中的创新应用的有效性和安全性.六个犬被用作实验单元，使用的犬单位的品种是小猎犬。每个犬科动物充当其自己的对照以最小化实验单元的数量。内镜摘除术,由一名外科医生执行，包括摘除左半前列腺，留下右下摆前列腺作为对照。在整个研究期间，所有犬科动物都保持着良好的健康状况。在所有6只犬中均未观察到不良事件。术后,没有发红的迹象,肿胀,或手术部位的其他不良反应。在主要器官的外观和形态中未观察到异常。前列腺和膀胱，为了进一步的病理评估，没有表现出大小异常，颜色,或纹理。未观察到异常或炎症，组织没有粘连，表明成功治愈。总之,我们的术前和术后参数的比较表明，IGBT脉冲激光，在100W的功率设置下，展示了安全的特点，功效,组织损伤最小,术后无重大并发症。这项研究为未来在人类环境中的应用奠定了理论基础，鼓励进一步探索IGBT钬激光在临床实践中的潜力。
