PDF(Pubmed)
Abstract：
UNASSIGNED: Intrathecal morphine (ITM) or erector spinae plane (ESP) block reduces postsurgical pain in patients who underwent kidney transplantation surgeries. We aimed to compare the effectiveness of both modalities in terms of duration and quality of postoperative analgesia along with postoperative fentanyl consumption.
UNASSIGNED: We conducted a randomised study and analysed 60 patients posted for elective live-related kidney transplantation surgery. They were randomised into two groups. Group M patients received ITM, whereas Group E patients received ESP block. We standardised the postoperative analgesia for both groups with intravenous fentanyl-based patient-controlled analgesia. The primary outcome was to compare the quality of analgesia using the numerical rating scale score between the groups. The secondary outcome was to observe the effect of both modalities on the duration of analgesia, postoperative fentanyl consumption, rescue analgesics requirement, catheter-related bladder discomfort and any complications.
UNASSIGNED: We found significantly lower pain scores at rest and while coughing in Group M at all time intervals, except at 24 h while coughing. The mean time to first analgesia requirement was significantly longer in Group M than in Group E (P = 0.002). No significant difference was found in postoperative consumption of total fentanyl (P = 0.065) and rescue analgesia in both groups. In Group M, there was significantly more nausea, vomiting and pruritus (P = 0.001).
UNASSIGNED: ITM provides long-lasting postoperative analgesia at the cost of higher side effects than ESP block.
UNASSIGNED: We conducted a randomised study and analysed 60 patients posted for elective live-related kidney transplantation surgery. They were randomised into two groups. Group M patients received ITM, whereas Group E patients received ESP block. We standardised the postoperative analgesia for both groups with intravenous fentanyl-based patient-controlled analgesia. The primary outcome was to compare the quality of analgesia using the numerical rating scale score between the groups. The secondary outcome was to observe the effect of both modalities on the duration of analgesia, postoperative fentanyl consumption, rescue analgesics requirement, catheter-related bladder discomfort and any complications.
UNASSIGNED: We found significantly lower pain scores at rest and while coughing in Group M at all time intervals, except at 24 h while coughing. The mean time to first analgesia requirement was significantly longer in Group M than in Group E (P = 0.002). No significant difference was found in postoperative consumption of total fentanyl (P = 0.065) and rescue analgesia in both groups. In Group M, there was significantly more nausea, vomiting and pruritus (P = 0.001).
UNASSIGNED: ITM provides long-lasting postoperative analgesia at the cost of higher side effects than ESP block.
摘要：
■鞘内注射吗啡（ITM）或竖脊肌平面（ESP）阻滞可减少接受肾移植手术的患者的术后疼痛。我们旨在比较两种方式在术后镇痛的持续时间和质量以及术后芬太尼消耗方面的有效性。
■我们进行了一项随机研究，分析了60名接受择期活体相关肾移植手术的患者。他们被随机分为两组。M组患者接受ITM，而E组患者接受ESP阻滞.我们使用基于芬太尼的静脉患者自控镇痛对两组的术后镇痛进行了标准化。主要结果是使用数字评定量表评分比较两组之间的镇痛质量。次要结果是观察两种方式对镇痛持续时间的影响，术后芬太尼消耗，抢救镇痛药的要求，导管相关的膀胱不适和任何并发症。
■我们发现M组在所有时间间隔休息和咳嗽时的疼痛评分明显降低，除了咳嗽时的24小时。M组首次镇痛的平均时间明显长于E组（P=0.002）。两组患者术后总芬太尼用量(P=0.065)和抢救镇痛差异无统计学意义。在M组中,有明显更多的恶心，呕吐和瘙痒（P=0.001）。
■ITM以比ESP阻滞更高的副作用为代价提供了持久的术后镇痛。
■我们进行了一项随机研究，分析了60名接受择期活体相关肾移植手术的患者。他们被随机分为两组。M组患者接受ITM，而E组患者接受ESP阻滞.我们使用基于芬太尼的静脉患者自控镇痛对两组的术后镇痛进行了标准化。主要结果是使用数字评定量表评分比较两组之间的镇痛质量。次要结果是观察两种方式对镇痛持续时间的影响，术后芬太尼消耗，抢救镇痛药的要求，导管相关的膀胱不适和任何并发症。
■我们发现M组在所有时间间隔休息和咳嗽时的疼痛评分明显降低，除了咳嗽时的24小时。M组首次镇痛的平均时间明显长于E组（P=0.002）。两组患者术后总芬太尼用量(P=0.065)和抢救镇痛差异无统计学意义。在M组中,有明显更多的恶心，呕吐和瘙痒（P=0.001）。
■ITM以比ESP阻滞更高的副作用为代价提供了持久的术后镇痛。
