PDF(Pubmed)
Abstract：
A 65-year-old male with a history of multiple myeloma and melanoma presented to the hospital with shortness of breath and lightheadedness. He was subsequently diagnosed with mild superior vena cava (SVC) syndrome due to a metastatic melanoma mediastinal mass. While melanoma frequently metastasizes to the lungs, the occurrence of SVC syndrome resulting from metastatic melanoma is exceedingly rare compared to other malignancies like lung cancer. Consequently, data on the incidence or prevalence of SVC syndrome caused by metastatic melanoma are sparse and variable. This case particularly underscores the rarity of melanoma causing SVC syndrome, as evidenced by the oncology team\'s request to perform a second biopsy to confirm the diagnosis. This case also highlights the need for a tailored diagnostic and management approach, providing valuable insights into the diverse presentations of melanoma and enriching the medical literature on this subject.
摘要：
一名65岁的男性，有多发性骨髓瘤和黑色素瘤病史，因呼吸急促和头昏眼花出现在医院。随后，由于转移性黑色素瘤纵隔肿块，他被诊断出患有轻度上腔静脉（SVC）综合征。虽然黑色素瘤经常转移到肺部，与肺癌等其他恶性肿瘤相比,由转移性黑色素瘤引起的SVC综合征的发生极为罕见.因此,关于转移性黑色素瘤引起的SVC综合征的发病率或患病率的数据是稀疏且可变的.这个病例特别突出了导致SVC综合征的黑色素瘤的罕见性，肿瘤学团队要求进行第二次活检以确认诊断。这一案例也凸显了对量身定制的诊断和管理方法的需求,为黑色素瘤的各种表现提供有价值的见解，并丰富有关该主题的医学文献。
