关键词: bisphosphonates case report lactation magnetic resonance imaging pregnancy prognosis transient osteoporosis

来  源:   DOI:10.7759/cureus.63509   PDF(Pubmed)

Abstract:
Transient pregnancy-related osteoporosis of the hip is a rare, idiopathic, benign, and usually self-limiting condition caused by edema of the bone marrow, which can be visualized on magnetic resonance imaging. Bilateral localization of the disease is even less common. Our case concerns a 31-year-old primigravida who, during the 35th week of pregnancy, was hospitalized at the Obstetrics and Gynecology Clinic of the General Hospital of Trikala with lumbar and hip pain. The pain gradually increased in intensity and was accompanied by severe movement limitation. No history of falls or injury was reported. Her personal history was unremarkable, and the course of the pregnancy was uneventful. A clinical examination by a team of orthopedic surgeons established a diagnosis of acute hip and back pain. Rest and administration of paracetamol did not improve her clinical condition. During the postpartum and lactation period, the lack of symptom relief led to the decision to further evaluate the patient. The diagnosis of pregnancy-related transient osteoporosis of both hips was established by magnetic resonance imaging. Immediate treatment with bisphosphonate medication after the discontinuation of breastfeeding led to a definitive remission of the symptoms three months later. In this study, after the case description, a brief literature review of this rare clinical entity is presented. Proper knowledge of this condition helps to provide the best possible short- and long-term prognostic outcomes for the mother, fetus, and newborn.
摘要:
短暂性妊娠相关的髋部骨质疏松症是一种罕见的,特发性,良性,通常是由骨髓水肿引起的自限性疾病,可以在磁共振成像上可视化。该疾病的双侧定位更不常见。我们的案件涉及一名31岁的primigravida,在怀孕的第35周,因腰椎和髋部疼痛在Trikala总医院妇产科诊所住院。疼痛强度逐渐增加,并伴有严重的运动受限。无跌倒或受伤史报道。她的个人历史并不引人注目,怀孕的过程很顺利。一组整形外科医生的临床检查确定了急性髋部和背部疼痛的诊断。休息和服用扑热息痛并不能改善她的临床状况。在产后和哺乳期,由于缺乏症状缓解,我们决定对患者进行进一步评估.通过磁共振成像建立了妊娠相关的两髋短暂性骨质疏松症的诊断。停止母乳喂养后立即使用双膦酸盐药物治疗可在三个月后最终缓解症状。在这项研究中,在案例描述之后,对这种罕见的临床实体进行了简短的文献综述。正确了解这种情况有助于为母亲提供最佳的短期和长期预后结果,胎儿,新生儿
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