PDF(Pubmed)
Abstract：
UNASSIGNED: T-wave inversions on electrocardiograms (ECGs) indicate a variety of conditions, such as coronary artery disease, myocarditis, and cardiomyopathy. Pulmonary artery stenosis (PAS) and pulmonary hypertension (PH) may cause right ventricular enlargement and ischaemia, which are reflected as T-wave inversions on ECGs. Continuous ECG monitoring is crucial for detecting dynamic changes indicative of PAS progression and reversal in right heart remodelling.
UNASSIGNED: This report presents the case of a young woman who experienced exertional dyspnoea for 5 years with ECG findings showing T-wave inversions across multiple leads. The patient was diagnosed with PAS and PH caused by Takayasu arteritis (TA). Following three successful balloon pulmonary angioplasty sessions, the patient exhibited significant clinical improvement, including the remission of PAS and PH. Throughout a 59-month cumulative follow-up period, the sustained effectiveness of the treatment was evidenced by the regression of right heart remodelling, as manifested in the normalization of the initially inverted T-waves on the ECG.
UNASSIGNED: Electrocardiogram changes, including right axis deviation, right bundle branch block, a deep S wave in lead I (R/S < 1), and a prominent R wave in lead aVR (R/Q > 1), have been termed PAS syndrome, often linked to TA-associated PAS, especially in young East Asian females. Early diagnosis is crucial but challenging due to atypical symptoms. The non-invasive ECG is vital for detection, with balloon pulmonary angioplasty serving as an effective treatment for TA-induced PAS when surgery is not an option, improving outcomes and potentially reversing right heart remodelling.
UNASSIGNED: This report presents the case of a young woman who experienced exertional dyspnoea for 5 years with ECG findings showing T-wave inversions across multiple leads. The patient was diagnosed with PAS and PH caused by Takayasu arteritis (TA). Following three successful balloon pulmonary angioplasty sessions, the patient exhibited significant clinical improvement, including the remission of PAS and PH. Throughout a 59-month cumulative follow-up period, the sustained effectiveness of the treatment was evidenced by the regression of right heart remodelling, as manifested in the normalization of the initially inverted T-waves on the ECG.
UNASSIGNED: Electrocardiogram changes, including right axis deviation, right bundle branch block, a deep S wave in lead I (R/S < 1), and a prominent R wave in lead aVR (R/Q > 1), have been termed PAS syndrome, often linked to TA-associated PAS, especially in young East Asian females. Early diagnosis is crucial but challenging due to atypical symptoms. The non-invasive ECG is vital for detection, with balloon pulmonary angioplasty serving as an effective treatment for TA-induced PAS when surgery is not an option, improving outcomes and potentially reversing right heart remodelling.
摘要：
■心电图（ECG）上的T波倒置表示各种情况，比如冠状动脉疾病，心肌炎,和心肌病。肺动脉狭窄(PAS)和肺动脉高压(PH)可引起右心室扩大和局部缺血,在心电图上被反射为T波反转。连续ECG监测对于检测指示PAS进展和右心重塑逆转的动态变化至关重要。
■本报告介绍了一个年轻女性经历5年劳力性呼吸困难的病例，心电图发现显示多个导联的T波倒置。患者被诊断为由大动脉炎（TA）引起的PAS和PH。经过三次成功的球囊肺血管成形术，患者表现出显著的临床改善，包括PAS和PH的缓解。在59个月的累计随访期内，右心重塑的消退证明了治疗的持续有效性，表现在心电图上最初倒置的T波正常化。
■心电图改变，包括右轴偏差，右束支传导阻滞,I导联中的深S波（R/S<1），以及AVR铅中突出的R波(R/Q>1)，被称为PAS综合征，通常与TA相关的PAS相关联，尤其是年轻的东亚女性。早期诊断至关重要，但由于症状不典型，因此具有挑战性。无创心电图对于检测至关重要，当手术不是一种选择时，球囊肺血管成形术可作为TA诱导的PAS的有效治疗方法，改善结果并可能逆转右心重塑。
■本报告介绍了一个年轻女性经历5年劳力性呼吸困难的病例，心电图发现显示多个导联的T波倒置。患者被诊断为由大动脉炎（TA）引起的PAS和PH。经过三次成功的球囊肺血管成形术，患者表现出显著的临床改善，包括PAS和PH的缓解。在59个月的累计随访期内，右心重塑的消退证明了治疗的持续有效性，表现在心电图上最初倒置的T波正常化。
■心电图改变，包括右轴偏差，右束支传导阻滞,I导联中的深S波（R/S<1），以及AVR铅中突出的R波(R/Q>1)，被称为PAS综合征，通常与TA相关的PAS相关联，尤其是年轻的东亚女性。早期诊断至关重要，但由于症状不典型，因此具有挑战性。无创心电图对于检测至关重要，当手术不是一种选择时，球囊肺血管成形术可作为TA诱导的PAS的有效治疗方法，改善结果并可能逆转右心重塑。
