利用肠道色氨酸分解代谢缓解小鼠动脉粥样硬化。
Mesh : Animals Tryptophan / metabolism Indoleamine-Pyrrole 2,3,-Dioxygenase / metabolism genetics Atherosclerosis / metabolism pathology genetics drug therapy Diet, High-Fat / adverse effects Mice Serotonin / metabolism Intestinal Mucosa / metabolism Mice, Inbred C57BL Kynurenine / metabolism Male Gastrointestinal Microbiome Indoles / pharmacology Inflammation / metabolism Mice, Knockout Intestines / pathology T-Lymphocytes / metabolism immunology Disease Models, Animal
来 源:
DOI:10.1038/s41467-024-50807-x
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