组织穿透纳米疗法靶向血管破坏剂处理的肿瘤微环境。
关键词: CA4P Peritoneal carcinomatosis Polymersomes Tumor-penetrating peptide Utorubicin Vascular disrupting agent iRGD
Mesh : Animals Tumor Microenvironment / drug effects Mice Female Nanoparticles / chemistry Bibenzyls / pharmacology chemistry Cell Line, Tumor Humans Stilbenes / pharmacology administration & dosage Oligopeptides / chemistry pharmacology Neuropilin-1 / metabolism Peritoneal Neoplasms / drug therapy Breast Neoplasms / drug therapy pathology metabolism Antineoplastic Agents / pharmacology administration & dosage
来 源:
DOI:10.1038/s41598-024-64610-7
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