关键词: Cutaneous T-cell lymphoma Lymphomatoid papulosis Mycosis fungoides Primary cutaneous anaplastic large cell lymphoma Sezary syndrome

Mesh : Humans Lymphoma, T-Cell, Cutaneous / diagnosis therapy pathology Skin Neoplasms / therapy diagnosis pathology Disease Management Mycosis Fungoides / diagnosis therapy pathology

来  源:   DOI:10.1016/j.hoc.2024.05.012

Abstract:
Cutaneous T-cell lymphoma is a group of non-Hodgkin T-cell lymphomas that develop in and affect the skin but can potentially spread to other organs. There are many subtypes, the most common of which are mycosis fungoides, Sezary syndrome, lymphomatoid papulosis, and primary cutaneous anaplastic large cell lymphoma. Cutaneous lymphoma is a common cause of recalcitrant chronic skin rash and notoriously mimics other dermatologic and hematologic conditions, often resulting in diagnostic delays of months to years. This review provides an introduction to cutaneous T-cell lymphoma, with a primary focus on the clinical presentation, diagnosis, immunopathogenesis, and management of the condition.
摘要:
皮肤T细胞淋巴瘤是一组非霍奇金T细胞淋巴瘤,在皮肤中发展并影响皮肤,但可能扩散到其他器官。有许多亚型,其中最常见的是霉菌病,Sezary综合征,淋巴瘤样丘疹病,和原发性皮肤间变性大细胞淋巴瘤。皮肤淋巴瘤是顽固性慢性皮疹的常见原因,出了名地模仿其他皮肤病学和血液学疾病,通常导致数月至数年的诊断延迟。本文综述了皮肤T细胞淋巴瘤,主要关注临床表现,诊断,免疫发病机制,和管理的条件。
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