Abstract：
BACKGROUND: Interbody devices in anterior lumbar interbody fusion (ALIF) are currently a focus of innovation due to their potential to improve clinical outcomes. The purpose of the present study was to analyze complications and changes in spinopelvic parameters after ALIF with the novel Medacta MectaLIF interbody fusion device.
METHODS: Patients aged 18 to 80 years who underwent multilevel ALIF using this novel implant were identified. Demographic and surgical data were collected. Patients were divided into short- and long-fusion cohorts. A comparison of outcomes between the short- and long-fusion groups was performed using the Student t test for continuous variables and Fisher\'s exact test and the χ2 test for categorical variables. Analysis of the pre- vs postoperative radiographic data for the entire cohort was performed using the 2-tailed Student t test.
RESULTS: One hundred and eight patients met the inclusion criteria. No significant postoperative change was observed in L1-4 lumbar lordosis (LL). L1-S1 LL increased to a mean of 55.1 ± 12.8 (a mean change of 10.7 ± 14.5), and L4-S1 LL increased to a mean of 38.4 ± 8.7 (a mean increase of 7.5 ± 8.2), with pelvic incidence LL mismatch changing from 8.9 ± 15.1 to 1.1 ± 13.5 (n = 102). Related changes in sacral slope and pelvic tilt were also observed (33.0 ± 11.0 to 37.6 ± 10.9 and 19.6 ± 9.5 to 18.2 ± 9.1 [n = 103], respectively). Five patients (4.6%) experienced implant subsidence, 1 (0.9%) had implant migration, and 6 (5.6%) experienced a nonunion. There was no difference in the rates of complications associated with the novel implant in the short- and long-fusion cohorts.
CONCLUSIONS: This novel implant achieves correction of spinopelvic parameters with minimal complications. The ability to modify the implant intraoperatively based on the patient\'s anatomy can help achieve maximal contact area and therefore help reduce the risk of subsidence.
CONCLUSIONS: This modular implant can achieve correction of spinopelvic parameters with minimal medical and surgical complications.
METHODS:
METHODS: Patients aged 18 to 80 years who underwent multilevel ALIF using this novel implant were identified. Demographic and surgical data were collected. Patients were divided into short- and long-fusion cohorts. A comparison of outcomes between the short- and long-fusion groups was performed using the Student t test for continuous variables and Fisher\'s exact test and the χ2 test for categorical variables. Analysis of the pre- vs postoperative radiographic data for the entire cohort was performed using the 2-tailed Student t test.
RESULTS: One hundred and eight patients met the inclusion criteria. No significant postoperative change was observed in L1-4 lumbar lordosis (LL). L1-S1 LL increased to a mean of 55.1 ± 12.8 (a mean change of 10.7 ± 14.5), and L4-S1 LL increased to a mean of 38.4 ± 8.7 (a mean increase of 7.5 ± 8.2), with pelvic incidence LL mismatch changing from 8.9 ± 15.1 to 1.1 ± 13.5 (n = 102). Related changes in sacral slope and pelvic tilt were also observed (33.0 ± 11.0 to 37.6 ± 10.9 and 19.6 ± 9.5 to 18.2 ± 9.1 [n = 103], respectively). Five patients (4.6%) experienced implant subsidence, 1 (0.9%) had implant migration, and 6 (5.6%) experienced a nonunion. There was no difference in the rates of complications associated with the novel implant in the short- and long-fusion cohorts.
CONCLUSIONS: This novel implant achieves correction of spinopelvic parameters with minimal complications. The ability to modify the implant intraoperatively based on the patient\'s anatomy can help achieve maximal contact area and therefore help reduce the risk of subsidence.
CONCLUSIONS: This modular implant can achieve correction of spinopelvic parameters with minimal medical and surgical complications.
METHODS:
摘要：
背景：腰椎前路椎间融合术（ALIF）中的椎间器械由于其改善临床结果的潜力，目前是创新的焦点。本研究的目的是使用新型MedactaMectaLIF椎间融合器分析ALIF后的并发症和脊柱骨盆参数的变化。
方法：确定使用这种新型植入物接受多级ALIF的18至80岁患者。收集人口统计学和手术数据。患者分为短期和长期融合队列。使用连续变量的Studentt检验和分类变量的Fisher精确检验和χ2检验对短融合组和长融合组之间的结果进行比较。使用2尾Studentt检验对整个队列的术前和术后影像学数据进行分析。
结果：108名患者符合纳入标准。L1-4腰椎前凸（LL）术后无明显变化。L1-S1LL增加到平均55.1±12.8（平均变化10.7±14.5），L4-S1LL平均增加到38.4±8.7（平均增加7.5±8.2），骨盆发病率LL不匹配从8.9±15.1变为1.1±13.5(n=102)。还观察到骶骨倾斜和骨盆倾斜的相关变化（33.0±11.0至37.6±10.9和19.6±9.5至18.2±9.1[n=103]，分别)。五名患者(4.6%)经历了植入物下沉，1（0.9%）有植入物迁移，和6（5.6％）经历了不愈合。在短融合和长融合队列中，与新型植入物相关的并发症发生率没有差异。
结论：这种新型植入物以最小的并发症实现了脊柱骨盆参数的校正。术中根据患者的解剖结构修改植入物的能力可以帮助获得最大的接触面积，因此有助于降低下沉的风险。
结论：这种模块化植入物可以在最小的医疗和手术并发症下实现脊柱骨盆参数的校正。
方法：
方法：确定使用这种新型植入物接受多级ALIF的18至80岁患者。收集人口统计学和手术数据。患者分为短期和长期融合队列。使用连续变量的Studentt检验和分类变量的Fisher精确检验和χ2检验对短融合组和长融合组之间的结果进行比较。使用2尾Studentt检验对整个队列的术前和术后影像学数据进行分析。
结果：108名患者符合纳入标准。L1-4腰椎前凸（LL）术后无明显变化。L1-S1LL增加到平均55.1±12.8（平均变化10.7±14.5），L4-S1LL平均增加到38.4±8.7（平均增加7.5±8.2），骨盆发病率LL不匹配从8.9±15.1变为1.1±13.5(n=102)。还观察到骶骨倾斜和骨盆倾斜的相关变化（33.0±11.0至37.6±10.9和19.6±9.5至18.2±9.1[n=103]，分别)。五名患者(4.6%)经历了植入物下沉，1（0.9%）有植入物迁移，和6（5.6％）经历了不愈合。在短融合和长融合队列中，与新型植入物相关的并发症发生率没有差异。
结论：这种新型植入物以最小的并发症实现了脊柱骨盆参数的校正。术中根据患者的解剖结构修改植入物的能力可以帮助获得最大的接触面积，因此有助于降低下沉的风险。
结论：这种模块化植入物可以在最小的医疗和手术并发症下实现脊柱骨盆参数的校正。
方法：
