PDF(Pubmed)
Abstract：
UNASSIGNED: Current methods evaluating tissue ischemia are based mainly on evaluating blood flow and not tissue perfusion. However, diabetes mainly affects small vessels and blood flow evaluation is insufficient. The aim of the trial was to evaluate the feasibility of NIRS in measuring perfusion changes during chronic total occlusion (CTO) revascularization in below the knee (BTK) arteries.
UNASSIGNED: A prospective observational study was performed. During the endovascular revascularization procedure, tissue oxygenation changes were measured using three NIRS sensors. Postoperative angiographies and 30 days wound healing was evaluated.
UNASSIGNED: The study enrolled 30 patients with chronic limb threatening ischemia, occluded below the knee arteries, Rutherford 5. Mean age 74.7 ± 11.2 years, 16 (53%) of the patients had diabetes mellitus, 10 (33%) had end-stage renal disease. A statistically significant NIRS rSO 2 increase was observed on sensors near the wound after the revascularization, p = 0.001. Thirty days follow-up visits included 27 patients, because 3 patients had died. Comparing good wound healing group with poor wound healing group intraoperative NIRS rSO 2 increase difference was statistically significant, p = 0.017.
UNASSIGNED: The study confirmed tissue perfusion increase could be detected using NIRS during revascularization of below the knee arteries. An intraoperative increase of NIRS rSO 2 proved to predict wound healing results.
UNASSIGNED: A prospective observational study was performed. During the endovascular revascularization procedure, tissue oxygenation changes were measured using three NIRS sensors. Postoperative angiographies and 30 days wound healing was evaluated.
UNASSIGNED: The study enrolled 30 patients with chronic limb threatening ischemia, occluded below the knee arteries, Rutherford 5. Mean age 74.7 ± 11.2 years, 16 (53%) of the patients had diabetes mellitus, 10 (33%) had end-stage renal disease. A statistically significant NIRS rSO 2 increase was observed on sensors near the wound after the revascularization, p = 0.001. Thirty days follow-up visits included 27 patients, because 3 patients had died. Comparing good wound healing group with poor wound healing group intraoperative NIRS rSO 2 increase difference was statistically significant, p = 0.017.
UNASSIGNED: The study confirmed tissue perfusion increase could be detected using NIRS during revascularization of below the knee arteries. An intraoperative increase of NIRS rSO 2 proved to predict wound healing results.
摘要：
■当前评估组织缺血的方法主要基于评估血流而不是组织灌注。然而,糖尿病主要影响小血管和血流评估不足。该试验的目的是评估NIRS在测量膝关节以下（BTK）动脉慢性完全闭塞（CTO）血运重建过程中灌注变化的可行性。
■进行了一项前瞻性观察性研究。在血管内血运重建过程中,使用三个NIRS传感器测量组织氧合变化.评估术后血管造影和30天伤口愈合。
■该研究纳入了30例慢性威胁肢体缺血患者，阻塞在膝盖动脉以下，卢瑟福5号.平均年龄74.7±11.2岁，16例（53%）患者患有糖尿病，10例(33%)有终末期肾病。血运重建后，在伤口附近的传感器上观察到有统计学意义的NIRSrSO2增加，p=0.001。30天的随访包括27名患者，因为3名患者死亡。比较伤口愈合良好组与伤口愈合不良组术中NIRSrSO2升高差异有统计学意义,p=0.017。
■该研究证实，在膝下动脉血运重建过程中，NIRS可检测到组织灌注增加。术中NIRSrSO2的增加被证明可以预测伤口愈合的结果。
■进行了一项前瞻性观察性研究。在血管内血运重建过程中,使用三个NIRS传感器测量组织氧合变化.评估术后血管造影和30天伤口愈合。
■该研究纳入了30例慢性威胁肢体缺血患者，阻塞在膝盖动脉以下，卢瑟福5号.平均年龄74.7±11.2岁，16例（53%）患者患有糖尿病，10例(33%)有终末期肾病。血运重建后，在伤口附近的传感器上观察到有统计学意义的NIRSrSO2增加，p=0.001。30天的随访包括27名患者，因为3名患者死亡。比较伤口愈合良好组与伤口愈合不良组术中NIRSrSO2升高差异有统计学意义,p=0.017。
■该研究证实，在膝下动脉血运重建过程中，NIRS可检测到组织灌注增加。术中NIRSrSO2的增加被证明可以预测伤口愈合的结果。
