关键词: colorectal liver metastasis laparoscopic liver resection minimally invasive surgery open liver resection outcomes

来  源:   DOI:10.3389/fonc.2024.1340430   PDF(Pubmed)

Abstract:
UNASSIGNED: This study comprehensively compared laparoscopic liver resection (LLR) to open liver resection (OLR) in treating colorectal cancer liver metastasis (CRLM).
UNASSIGNED: A systematic review of relevant literature was conducted to assess a range of crucial surgical and oncological outcomes.
UNASSIGNED: Findings indicate that minimally invasive surgery (MIS) did not significantly prolong the duration of surgery compared to open liver resection and notably demonstrated lower blood transfusion rates and reduced intraoperative blood loss. While some studies favored MIS for its lower complication rates, others did not establish a statistically significant difference. One study identified a lower post-operative mortality rate in the MIS group. Furthermore, MIS consistently correlated with shorter hospital stays, indicative of expedited post-operative recovery. Concerning oncological outcomes, while certain meta-analyses reported a lower rate of cancer recurrence in the MIS group, others found no significant disparity. Overall survival and disease-free survival remained comparable between the MIS and open liver resection groups.
UNASSIGNED: The analysis emphasizes the potential advantages of LLR in terms of surgical outcomes and aligns with existing literature findings in this field.
UNASSIGNED: [website], identifier [registration number].
摘要:
本研究比较了腹腔镜肝切除术(LLR)与开腹肝切除术(OLR)治疗结直肠癌肝转移(CRLM)的疗效。
对相关文献进行了系统综述,以评估一系列重要的手术和肿瘤结局。
研究结果表明,与开腹肝切除术相比,微创手术(MIS)并未显著延长手术时间,并且显著降低输血率和减少术中失血量。虽然一些研究支持MIS较低的并发症发生率,其他人没有建立统计学上的显著差异.一项研究发现,MIS组术后死亡率较低。此外,MIS始终与住院时间较短相关,表明术后恢复加快。关于肿瘤学结果,虽然某些荟萃分析报告MIS组的癌症复发率较低,其他人没有发现明显的差异。MIS和开放肝切除组之间的总生存率和无病生存率保持相当。
分析强调了LLR在手术结果方面的潜在优势,并与该领域的现有文献发现保持一致。
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