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Abstract：
UNASSIGNED: Exercise capacity serves as a direct representation of cardiac function. The Duke Activity Status Index (DASI), a self-administered 12-item questionnaire, covers aspects of daily living, household tasks, sexual function, and physical activity. Although widely used to evaluate exercise capacity, its validation in Chinese cardiovascular disease (CVD) patients has not been thoroughly explored. Considering the significant cultural and lifestyle differences between China and Western countries, which may influence Chinese patients\' comprehension and responses to DASI, our objective is to culturally adapt DASI for Chinese patients with CVD to ensure its precision in assessing exercise capacity.
UNASSIGNED: The cultural adaptation of the original DASI questionnaire into Chinese followed a rigorous process to ensure its validity, reliability, and sensitivity to Chinese CVD patients. The study included 107 outpatients diagnosed with CVD who completed the DASI and cardiopulmonary exercise testing (CPET). Cronbach\'s alpha, Spearman correlation, and factor analysis were utilized to test reliability and validity. Receiver operating characteristic (ROC) curve analysis was employed to assess the prognostic utility of the DASI.
UNASSIGNED: Participants had a mean DASI score of 39.40 ± 10.75 and a peak oxygen uptake (Peak VO 2 ) of 19.53 ± 5.89 mL/min/kg. The Chinese version of the DASI exhibited satisfactory reliability and validity in CVD patients, with a Chronbach\'s alpha coefficient of 0.706. The DASI score demonstrated a moderate correlation with Peak VO 2 measured by CPET (r = 0.67, p < 0.001). Factor analysis yielded three factors, accounting for 56.76% of the total variance, with factor 1 contributing to 26.38% of the variance. ROC curve analysis demonstrated that the DASI exhibited discriminative utility in the identification of patients with improved long-term prognosis (p < 0.001). The ROC curve had an area of 0.788 [95% confidence interval (CI) = 0.704-0.871]. The DASI score ≥ 36.85 served as the optimal threshold for enhanced long-term prognosis, exhibiting a sensitivity of 0.80 and a specificity of 0.69.
UNASSIGNED: The culturally adapted DASI questionnaire is a straightforward and efficient tool for reasonably evaluating exercise capacity in Chinese CVD patients.
UNASSIGNED: The cultural adaptation of the original DASI questionnaire into Chinese followed a rigorous process to ensure its validity, reliability, and sensitivity to Chinese CVD patients. The study included 107 outpatients diagnosed with CVD who completed the DASI and cardiopulmonary exercise testing (CPET). Cronbach\'s alpha, Spearman correlation, and factor analysis were utilized to test reliability and validity. Receiver operating characteristic (ROC) curve analysis was employed to assess the prognostic utility of the DASI.
UNASSIGNED: Participants had a mean DASI score of 39.40 ± 10.75 and a peak oxygen uptake (Peak VO 2 ) of 19.53 ± 5.89 mL/min/kg. The Chinese version of the DASI exhibited satisfactory reliability and validity in CVD patients, with a Chronbach\'s alpha coefficient of 0.706. The DASI score demonstrated a moderate correlation with Peak VO 2 measured by CPET (r = 0.67, p < 0.001). Factor analysis yielded three factors, accounting for 56.76% of the total variance, with factor 1 contributing to 26.38% of the variance. ROC curve analysis demonstrated that the DASI exhibited discriminative utility in the identification of patients with improved long-term prognosis (p < 0.001). The ROC curve had an area of 0.788 [95% confidence interval (CI) = 0.704-0.871]. The DASI score ≥ 36.85 served as the optimal threshold for enhanced long-term prognosis, exhibiting a sensitivity of 0.80 and a specificity of 0.69.
UNASSIGNED: The culturally adapted DASI questionnaire is a straightforward and efficient tool for reasonably evaluating exercise capacity in Chinese CVD patients.
摘要：
■运动能力是心脏功能的直接代表。杜克大学活动状态指数(DASI)一份自我管理的12项问卷，涵盖日常生活的各个方面，家务,性功能,和身体活动。虽然广泛用于评估运动能力，其在中国心血管疾病（CVD）患者中的有效性尚未得到彻底探索。考虑到中国和西方国家的文化和生活方式的显著差异，这可能会影响中国患者对DASI的理解和反应，我们的目标是在文化上适应中国CVD患者的DASI,以确保其评估运动能力的准确性.
■原始DASI问卷的文化适应中文遵循严格的过程，以确保其有效性，可靠性,以及对中国CVD患者的敏感性。该研究包括107名诊断为CVD的门诊患者，他们完成了DASI和心肺运动测试（CPET）。Cronbach的阿尔法,斯皮尔曼相关性，并采用因子分析进行信度和效度检验。采用受试者工作特征(ROC)曲线分析来评估DASI的预后效用。
■参与者的平均DASI评分为39.40±10.75，峰值摄氧量（峰值VO2）为19.53±5.89mL/min/kg。中文版DASI在CVD患者中表现出令人满意的信度和效度，Chronbach的α系数为0.706。DASI评分与CPET测得的峰值VO2呈中等相关性（r=0.67，p<0.001）。因子分析产生了三个因素，占总方差的56.76%，因子1贡献了26.38%的方差。ROC曲线分析表明，DASI在鉴定长期预后改善的患者中表现出判别效用（p<0.001）。ROC曲线面积为0.788[95%置信区间(CI)=0.704-0.871]。DASI评分≥36.85是增强长期预后的最佳阈值，表现出0.80的灵敏度和0.69的特异性。
■文化适应的DASI问卷是合理评估中国心血管疾病患者运动能力的简单而有效的工具。
■原始DASI问卷的文化适应中文遵循严格的过程，以确保其有效性，可靠性,以及对中国CVD患者的敏感性。该研究包括107名诊断为CVD的门诊患者，他们完成了DASI和心肺运动测试（CPET）。Cronbach的阿尔法,斯皮尔曼相关性，并采用因子分析进行信度和效度检验。采用受试者工作特征(ROC)曲线分析来评估DASI的预后效用。
■参与者的平均DASI评分为39.40±10.75，峰值摄氧量（峰值VO2）为19.53±5.89mL/min/kg。中文版DASI在CVD患者中表现出令人满意的信度和效度，Chronbach的α系数为0.706。DASI评分与CPET测得的峰值VO2呈中等相关性（r=0.67，p<0.001）。因子分析产生了三个因素，占总方差的56.76%，因子1贡献了26.38%的方差。ROC曲线分析表明，DASI在鉴定长期预后改善的患者中表现出判别效用（p<0.001）。ROC曲线面积为0.788[95%置信区间(CI)=0.704-0.871]。DASI评分≥36.85是增强长期预后的最佳阈值，表现出0.80的灵敏度和0.69的特异性。
■文化适应的DASI问卷是合理评估中国心血管疾病患者运动能力的简单而有效的工具。
