关键词: acquired immunodeficiency syndrome bacillary angiomatosis bartonella henselae hiv mycobacterium avium complex

来  源:   DOI:10.7759/cureus.63392   PDF(Pubmed)

Abstract:
Bartonella is a genus of arthropod-borne bacterial pathogens that typically cause persistent infections of erythrocytes and endothelial cells in mammalian hosts. The species that primarily infect humans are Bartonella henselae and Bartonella quintana. Depending on immune status, the clinical presentation of B. henselae may differ, manifesting as cat-scratch disease in immunocompetent individuals or bacillary angiomatosis (BA) and peliosis in immunocompromised patients. The cutaneous manifestations of BA are typically characterized by occasionally painful, angiomatous papules and nodules, often with a chronic, persistent course. Herein, we present a case of biopsy-confirmed B. henselae infection in a 32-year-old HIV-positive female with acquired immunodeficiency syndrome in the setting of disseminated Mycobacterium avium complex infection, an association that has been less frequently described. This case serves as an important reminder to consider uncommon opportunistic infectious etiologies when examining immunocompromised patients, as prompt diagnosis and treatment are essential in this patient population.
摘要:
巴尔通体是一种节肢动物传播的细菌病原体,通常会导致哺乳动物宿主中红细胞和内皮细胞的持续感染。主要感染人类的物种是巴尔通体和巴尔通体。根据免疫状态,henselae的临床表现可能不同,在免疫功能正常的个体中表现为猫抓病或在免疫功能低下的患者中表现为杆菌血管瘤病(BA)和peliosis。BA的皮肤表现通常以偶尔疼痛为特征,血管瘤状丘疹和结节,经常患有慢性,持续的课程。在这里,我们介绍了一例32岁的HIV阳性女性患者在播散的鸟分枝杆菌复合感染的情况下经活检证实的Henselae感染。一个不太频繁描述的协会。此病例作为一个重要的提醒,在检查免疫功能低下的患者时,应考虑罕见的机会性感染病因。因为及时的诊断和治疗对这一患者人群至关重要。
公众号