关键词: COVID-19 SARS-CoV-2 cycle threshold immunocompromised infection control

来  源:   DOI:10.1093/ofid/ofae367   PDF(Pubmed)

Abstract:
Among 495 patients who were immunocompromised and tested positive for SARS-CoV-2, polymerase chain reaction cycle thresholds remained <33 beyond 20 days more frequently in patients with hematologic malignancies, particularly those receiving B-cell-depleting or Bruton tyrosine kinase inhibitor therapy, as compared with those with solid organ malignancy (26% vs 5%).
摘要:
在495例免疫功能低下且SARS-CoV-2检测阳性的患者中,在血液系统恶性肿瘤患者中,聚合酶链反应循环阈值在超过20天的时间内保持<33,特别是那些接受B细胞消耗或布鲁顿酪氨酸激酶抑制剂治疗的患者,与实体器官恶性肿瘤患者相比(26%vs5%)。
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