PDF(Pubmed)
Abstract：
Non-ST segment elevation myocardial infarction (NSTEMI) is the most frequent type of acute coronary syndrome in the elderly. Antithrombotic therapy is the cornerstone of pharmacological therapy in the setting of an acute ischemic event, a clinical scenario in which thrombotic and bleeding risks ought to be considered, particularly in older patients. In this article, specific aspects of antithrombotic therapy in elderly patients with NSTEMI are reviewed, including pharmacokinetic and pharmacodynamic characteristics and different clinical situations. The role of frailty and other common geriatric conditions, that are associated with worse prognosis in elderly patients with cardiovascular disease, is also addressed.
摘要：
非ST段抬高型心肌梗死(NSTEMI)是老年人最常见的急性冠脉综合征。抗血栓治疗是急性缺血事件背景下药物治疗的基石，应考虑血栓形成和出血风险的临床情况，尤其是老年患者。在这篇文章中,对老年NSTEMI患者抗栓治疗的具体方面进行了综述，包括药代动力学和药效学特征以及不同的临床情况。虚弱和其他常见的老年病的作用，这与老年心血管疾病患者的预后较差有关，也解决了。
