Abstract:
Head and neck cancer (HNC) shares some risk factors with cardiovascular disease. Neck radiotherapy (RT) causes carotid artery injury and stenosis. In HNC patients treated with RT, the prevalence rate of severe ( > 70%) carotid artery stenosis is > 10%, and the cumulative incidence continuously increases over time. There is at least a two-fold risk of cerebrovascular events in these patients compared with the normal population. Carotid artery stenosis is mainly assessed and diagnosed via duplex ultrasonography. Angioplasty and stenting may be recommended to patients who developed severe post-irradiation carotid artery stenosis. This review assessed Taiwanese data that provided some recommendations for HNC patients treated with RT. With consideration of the high prevalence rate of carotid artery stenosis after neck irradiation, duplex ultrasonography should be included in the follow-up workup.
摘要:
头颈癌(HNC)与心血管疾病有一些共同的危险因素。颈部放疗(RT)导致颈动脉损伤和狭窄。在接受RT治疗的HNC患者中,严重(>70%)颈动脉狭窄的患病率>10%,累积发病率随时间不断增加。与正常人群相比,这些患者发生脑血管事件的风险至少是两倍。颈动脉狭窄主要通过双工超声评估和诊断。血管成形术和支架术可推荐给发生严重照射后颈动脉狭窄的患者。这篇综述评估了台湾的数据,这些数据为接受RT治疗的HNC患者提供了一些建议。考虑到颈部照射后颈动脉狭窄的高患病率,后续检查中应包括双工超声检查。