UNASSIGNED: Forty-four consecutive patients [35 males, ejection fraction (EF) < 50%] with CHF under medication enrolled in a 36-session CR program and were randomized in two exercise groups; HIIT (HIIT group) or HIIT combined with strength training (high intensity interval training combined with strength training (COM) group). All patients underwent baseline and endpoint outcome measures of a symptom-limited maximal cardiopulmonary exercise testing (CPET), 1 repetition maximum (1RM) test, muscular endurance test, echocardiography, and Minnesota Living with Heart Failure Questionnaire (MLWHFQ).
UNASSIGNED: Most of the CPET indices, EF, 1RM test, muscular endurance and QoL were improved after the CR program in each exercise training group (p < 0.05). However, COM group demonstrated a further improvement in chest muscle testing and workload at anaerobic threshold (AT) compared to HIIT group.
UNASSIGNED: An exercise-based CR program, consisted of either HIIT or HIIT combined with strength training, improves FC and QoL of patients with CHF. However, the addition of strength training to HIIT seems to have further beneficial effects on chest muscle strength and endurance, as well as workload at AT.
UNASSIGNED: The study was registered in ClinicalTrials.gov with number NCT02387411.
■连续44名患者[35名男性,射血分数(EF)<50%]在36个疗程的CR计划中纳入药物治疗的CHF,并随机分为两个运动组;HIIT(HIIT组)或HIIT结合力量训练(高强度间歇训练结合力量训练(COM)组)。所有患者均接受症状受限最大心肺运动试验(CPET)的基线和终点结果测量,1次最大重复(1RM)试验,肌肉耐力测试,超声心动图,明尼苏达州心力衰竭生活问卷(MLWHFQ)。
■大多数CPET指数,EF,1RM试验,运动训练组采用CR后肌肉耐力和QoL均有改善(p<0.05)。然而,与HIIT组相比,COM组在无氧阈值(AT)的胸肌测试和工作量方面有进一步改善。
■基于运动的CR计划,包括HIIT或HIIT结合力量训练,改善CHF患者的FC和QoL。然而,在HIIT中加入力量训练似乎对胸部肌肉力量和耐力有进一步的有益影响,以及AT的工作量。
■该研究在ClinicalTrials.gov注册,编号为NCT02387411。