PDF(Pubmed)
Abstract：
Atrial fibrillation (AF) is one of the most common arrhythmias in medical practice. Diabetes mellitus (DM) is one of the independent risk factors for atrial fibrillation. The increased morbility of atrial fibrillation in diabetes mellitus is related to both structural and electrical remodeling of atrium. Based on studies of atrial electrophysiological changes in diabetes mellitus, this article focuses on the electrical remodeling of atrial cardiomyocytes, including remodeling of sodium channels, calcium channels, potassium channels and other channels, to provide the basis for the clinical management of antiarrhythmic drugs in diabetic patients with atrial fibrillation.
摘要：
心房颤动（AF）是医学实践中最常见的心律失常之一。糖尿病是房颤的独立危险因素之一。糖尿病患者心房颤动的发病率增加与心房结构和电重构有关。基于糖尿病心房电生理变化的研究，本文主要研究心房心肌细胞的电重构,包括钠通道的重塑，钙通道,钾通道和其他通道，为糖尿病合并房颤患者抗心律失常药物的临床管理提供依据。
