PDF(Pubmed)
Abstract：
UNASSIGNED: Few studies of middle-aged and older adults have examined the association between age and sleep using objective sleep measures. We examined these associations in adults aged ≥40 years using wrist actigraphy, and investigated whether these associations differed by sex and race.
UNASSIGNED: Participants were 468 cognitively normal adults aged ≥40 years enrolled in the Baltimore Longitudinal Study of Aging who completed wrist actigraphy. We used Generalized Least Squares Models to examine the associations of age with actigraphic sleep parameters, including total sleep time (TST), sleep efficiency, sleep onset latency, and wake after sleep onset (WASO). We conducted interaction and stratification analyses to test whether cross-sectional age-sleep associations were modified by sex and race.
UNASSIGNED: In analyses adjusting for sex, body mass index, and individual medical conditions, older age was associated with longer TST from ages 40-70 that plateaued after age 70. Older age also was associated with lower sleep efficiency, longer sleep onset latency, and greater WASO. In men only, after age 70, older age was associated with shorter TST, lower sleep efficiency, longer onset latency, and greater WASO. However, we did not observe any significant interactions of race with age.
UNASSIGNED: Older age was associated with longer TST from ages 40 to 70 and with poorer sleep quality after age 40, and these relationships might vary by sex. Future studies with larger sample sizes are needed to investigate mechanisms that may account for sex differences in the observed age-sleep associations.
UNASSIGNED: Participants were 468 cognitively normal adults aged ≥40 years enrolled in the Baltimore Longitudinal Study of Aging who completed wrist actigraphy. We used Generalized Least Squares Models to examine the associations of age with actigraphic sleep parameters, including total sleep time (TST), sleep efficiency, sleep onset latency, and wake after sleep onset (WASO). We conducted interaction and stratification analyses to test whether cross-sectional age-sleep associations were modified by sex and race.
UNASSIGNED: In analyses adjusting for sex, body mass index, and individual medical conditions, older age was associated with longer TST from ages 40-70 that plateaued after age 70. Older age also was associated with lower sleep efficiency, longer sleep onset latency, and greater WASO. In men only, after age 70, older age was associated with shorter TST, lower sleep efficiency, longer onset latency, and greater WASO. However, we did not observe any significant interactions of race with age.
UNASSIGNED: Older age was associated with longer TST from ages 40 to 70 and with poorer sleep quality after age 40, and these relationships might vary by sex. Future studies with larger sample sizes are needed to investigate mechanisms that may account for sex differences in the observed age-sleep associations.
摘要：
■很少有针对中老年人的研究使用客观的睡眠测量来检查年龄与睡眠之间的关系。我们使用腕动图检查了年龄≥40岁的成年人的这些关联，并调查这些关联是否因性别和种族而异。
■参与者是468名年龄≥40岁的认知正常成年人，他们参加了巴尔的摩纵向衰老研究，完成了腕关节肌动描记术。我们使用广义最小二乘模型来检查年龄与活动睡眠参数的关系，包括总睡眠时间（TST），睡眠效率，睡眠发作潜伏期，并在睡眠开始后醒来（WASO）。我们进行了相互作用和分层分析，以测试横截面年龄-睡眠关联是否因性别和种族而改变。
■在调整性别的分析中，身体质量指数,和个人医疗条件，年龄较大与40-70岁的TST较长相关,在70岁后趋于稳定.年龄较大也与睡眠效率较低有关，更长的睡眠发作潜伏期，和更大的WASO。只有男人，70岁以后，年龄较大与较短的TST相关，降低睡眠效率，更长的发作潜伏期，和更大的WASO。然而,我们没有观察到种族与年龄的任何显著交互作用.
■年龄较大与40至70岁的TST时间较长以及40岁以后的睡眠质量较差有关，这些关系可能因性别而异。未来的研究需要更大的样本量来调查可能解释观察到的年龄-睡眠关联中性别差异的机制。
■参与者是468名年龄≥40岁的认知正常成年人，他们参加了巴尔的摩纵向衰老研究，完成了腕关节肌动描记术。我们使用广义最小二乘模型来检查年龄与活动睡眠参数的关系，包括总睡眠时间（TST），睡眠效率，睡眠发作潜伏期，并在睡眠开始后醒来（WASO）。我们进行了相互作用和分层分析，以测试横截面年龄-睡眠关联是否因性别和种族而改变。
■在调整性别的分析中，身体质量指数,和个人医疗条件，年龄较大与40-70岁的TST较长相关,在70岁后趋于稳定.年龄较大也与睡眠效率较低有关，更长的睡眠发作潜伏期，和更大的WASO。只有男人，70岁以后，年龄较大与较短的TST相关，降低睡眠效率，更长的发作潜伏期，和更大的WASO。然而,我们没有观察到种族与年龄的任何显著交互作用.
■年龄较大与40至70岁的TST时间较长以及40岁以后的睡眠质量较差有关，这些关系可能因性别而异。未来的研究需要更大的样本量来调查可能解释观察到的年龄-睡眠关联中性别差异的机制。
