UNASSIGNED: To constitute the fracture group, data were collected retrospectively from patients with one or more recent osteoporotic vertebral fractures between T10 and L5 such as non-injected computerized tomography (CT), dual-energy X-ray absorptiometry (DXA). A control group was made by matching the patients on age, bone mineral density measured by DXA and gender. We analyzed PM and PVM atrophy based on cross-sectional area (CSA) adjusted to the body area as well as fatty infiltration on a 3-level scale and the average muscle density in Hounsfield units (HU).
UNASSIGNED: One hundred seventeen patients were included in each group. The fracture group had a lower PVM CSA than the control group (2197.92 ± 460.19 versus 2335.20 ± 394.42 mm2.m-2, respectively p = 0.015), but there was no significant difference in the PM (746.92 ± 197.89 versus 731.74 ± 215.53 mm2.m-2, respectively p = 0.575). The fracture group had a higher grade of fatty infiltration than the control group (PM: 1.3 ± 0.46 versus 1.07 ± 0.25, p < 0.001; PVM: 1.93 ± 0.5 versus 1.74 ± 0.5, p = 0.003) and a lower average muscle density (PM: 26.99 ± 12.83 versus 33.91 ± 8.12 HU, p < 0.001; PVM: 3.42 ± 21.06 versus 12.94 ± 18.88 HU, p < 0.001).
UNASSIGNED: This study shows an association between a lack of axial musculature and the occurrence of osteoporotic vertebral fractures. Preventive strengthening exercises could be proposed to osteoporotic patients.
■要构成骨折组,数据是回顾性收集从T10和L5之间的一个或多个最近的骨质疏松性椎体骨折的患者,如非注射计算机断层扫描(CT),双能X射线吸收法(DXA)。对照组是通过匹配患者的年龄,通过DXA和性别测量骨密度。我们根据根据身体面积调整的横截面积(CSA)以及3级尺度的脂肪浸润和以Hounsfield单位(HU)为单位的平均肌肉密度,分析了PM和PVM萎缩。
■每组包括117名患者。骨折组的PVMCSA低于对照组(2197.92±460.19对2335.20±394.42mm2。m-2,分别为p=0.015),但是PM没有显着差异(746.92±197.89与731.74±215.53mm2。m-2,分别为p=0.575)。骨折组的脂肪浸润程度高于对照组(PM:1.3±0.46对1.07±0.25,p<0.001;PVM:1.93±0.5对1.74±0.5,p=0.003),平均肌肉密度较低(PM:26.99±12.83对33.91±8.12HU,p<0.001;PVM:3.42±21.06对12.94±18.88HU,p<0.001)。
■这项研究表明,轴向肌肉组织的缺乏与骨质疏松性椎体骨折的发生之间存在关联。可对骨质疏松患者提出预防性加强练习。