PDF(Pubmed)
Abstract：
UNASSIGNED: Systemic Lupus Erythematosus (SLE) is an autoimmune disease with unknown etiology resulting in chronic multi-organ inflammation. Juvenile Systemic Lupus Erythematosus (JSLE) is a specific diagnosis of SLE in juvenile, characterized by oral ulceration.
UNASSIGNED: This case report attempts to provide information for oral medicine specialists in managing JSLE patients with hepatosplenomegaly.
UNASSIGNED: A 17-year-old female patient was referred from the Pediatrics Department with mouth ulcers accompanied by dry lips and a tendency to bleed. The most concerning lesion was located on the left buccal mucosa, a single ulceration measuring 5x6mm. Multiple ulcerations spread over the upper and lower labial mucosa, with haemorrhagic crusts on the lips. Painful ulceration can lead to difficulties in mouth opening and impaired function in eating and drinking. Central erythema was seen on the palate. Pseudomembranous candidiasis was also seen on the patient\'s tongue. The hepatosplenomegaly was confirmed by CT scan, with enzyme values of SGPT (386 U/L) and SGOT (504 U/L).
UNASSIGNED: Administration of 0.9% NaCl was instructed to the patient to maintain oral hygiene and help moisturize lips in order to remove haemorrhagic crusts. Administration of 0.025% hyaluronic acid mouthwash and topical steroid ointment mixture for ulcerated and inflammatory conditions. Drug adjustments were made based on laboratory tests and the patient\'s clinical condition was improving.
UNASSIGNED: Managing oral symptoms helps reduce morbidity in JSLE patients. Topical corticosteroids are considered the first line in controlling oral inflammation. Dentists play a role in improving patients\' oral hygiene with the aim of reducing the risk of other opportunistic infections.
UNASSIGNED: This case report attempts to provide information for oral medicine specialists in managing JSLE patients with hepatosplenomegaly.
UNASSIGNED: A 17-year-old female patient was referred from the Pediatrics Department with mouth ulcers accompanied by dry lips and a tendency to bleed. The most concerning lesion was located on the left buccal mucosa, a single ulceration measuring 5x6mm. Multiple ulcerations spread over the upper and lower labial mucosa, with haemorrhagic crusts on the lips. Painful ulceration can lead to difficulties in mouth opening and impaired function in eating and drinking. Central erythema was seen on the palate. Pseudomembranous candidiasis was also seen on the patient\'s tongue. The hepatosplenomegaly was confirmed by CT scan, with enzyme values of SGPT (386 U/L) and SGOT (504 U/L).
UNASSIGNED: Administration of 0.9% NaCl was instructed to the patient to maintain oral hygiene and help moisturize lips in order to remove haemorrhagic crusts. Administration of 0.025% hyaluronic acid mouthwash and topical steroid ointment mixture for ulcerated and inflammatory conditions. Drug adjustments were made based on laboratory tests and the patient\'s clinical condition was improving.
UNASSIGNED: Managing oral symptoms helps reduce morbidity in JSLE patients. Topical corticosteroids are considered the first line in controlling oral inflammation. Dentists play a role in improving patients\' oral hygiene with the aim of reducing the risk of other opportunistic infections.
摘要：
■系统性红斑狼疮（SLE）是一种病因不明的自身免疫性疾病，可导致慢性多器官炎症。青少年系统性红斑狼疮（JSLE）是青少年SLE的特异性诊断，以口腔溃疡为特征。
■本病例报告试图为口腔医学专家管理JSLE肝脾肿大患者提供信息。
一名17岁女性患者从儿科转诊，口腔溃疡伴有嘴唇干燥和出血倾向。最值得关注的病变位于左侧颊黏膜，单个溃疡测量5x6mm。多发溃疡遍布上下唇粘膜，嘴唇上有出血性结皮.疼痛的溃疡会导致张口困难和进食和饮水功能受损。上颚可见中央红斑。在患者的舌头上也发现了假膜性念珠菌病。CT扫描证实肝脾肿大，SGPT(386U/L)和SGOT(504U/L)的酶值。
■指示患者施用0.9%NaCl以保持口腔卫生并帮助滋润嘴唇以去除出血性结皮。给予0.025％透明质酸漱口水和局部类固醇软膏混合物治疗溃疡和炎症。根据实验室检查进行药物调整，患者的临床状况正在改善。
管理口腔症状有助于降低JSLE患者的发病率。局部皮质类固醇被认为是控制口腔炎症的第一线。牙医在改善患者口腔卫生方面发挥作用，目的是降低其他机会性感染的风险。
■本病例报告试图为口腔医学专家管理JSLE肝脾肿大患者提供信息。
一名17岁女性患者从儿科转诊，口腔溃疡伴有嘴唇干燥和出血倾向。最值得关注的病变位于左侧颊黏膜，单个溃疡测量5x6mm。多发溃疡遍布上下唇粘膜，嘴唇上有出血性结皮.疼痛的溃疡会导致张口困难和进食和饮水功能受损。上颚可见中央红斑。在患者的舌头上也发现了假膜性念珠菌病。CT扫描证实肝脾肿大，SGPT(386U/L)和SGOT(504U/L)的酶值。
■指示患者施用0.9%NaCl以保持口腔卫生并帮助滋润嘴唇以去除出血性结皮。给予0.025％透明质酸漱口水和局部类固醇软膏混合物治疗溃疡和炎症。根据实验室检查进行药物调整，患者的临床状况正在改善。
管理口腔症状有助于降低JSLE患者的发病率。局部皮质类固醇被认为是控制口腔炎症的第一线。牙医在改善患者口腔卫生方面发挥作用，目的是降低其他机会性感染的风险。
