PDF(Pubmed)
Abstract：
UNASSIGNED: Systematic evaluation of the effects of vitamin D supplementation in heart failure (HF) patients.
UNASSIGNED: Searches were conducted on National Library of Medicine, Web of Science, Cochrane Library, Google Scholar, China National Knowledge Infrastructure, and WANFANG databases. We analyzed data by using Review Manager 5.4 software. All are from the earliest records to March 2023. Outcome indicators analyzed the left ventricular ejection fraction (LVEF), the left ventricular end-diastolic internal diameter (LVEDD), the B-type brain natriuretic peptide (BNP) level and the 25-hydroxy vitamin D (25(OH)D) level.
UNASSIGNED: Ten studies with 1099 patients were included. LVEF (mean difference (MD) = 0.74, 95% CI: -0.29 to 1.76, p = 0.41), LVEDD (MD = -0.59, 95% CI: -1.83 to 0.66, p = 0.25), BNP (MD = -0.08, 95% CI: -0.24 to 0.08, p = 0.34), 25(OH)D (MD = 0.41, 95% CI: -0.28 to 1.11, p = 0.25) are not statistically significant. And there is no heterogeneity in the results of LVEF, LVEDD and BNP indicators.
UNASSIGNED: Vitamin D supplementation may not be helpful in the clinical management of patients with HF.
UNASSIGNED: Searches were conducted on National Library of Medicine, Web of Science, Cochrane Library, Google Scholar, China National Knowledge Infrastructure, and WANFANG databases. We analyzed data by using Review Manager 5.4 software. All are from the earliest records to March 2023. Outcome indicators analyzed the left ventricular ejection fraction (LVEF), the left ventricular end-diastolic internal diameter (LVEDD), the B-type brain natriuretic peptide (BNP) level and the 25-hydroxy vitamin D (25(OH)D) level.
UNASSIGNED: Ten studies with 1099 patients were included. LVEF (mean difference (MD) = 0.74, 95% CI: -0.29 to 1.76, p = 0.41), LVEDD (MD = -0.59, 95% CI: -1.83 to 0.66, p = 0.25), BNP (MD = -0.08, 95% CI: -0.24 to 0.08, p = 0.34), 25(OH)D (MD = 0.41, 95% CI: -0.28 to 1.11, p = 0.25) are not statistically significant. And there is no heterogeneity in the results of LVEF, LVEDD and BNP indicators.
UNASSIGNED: Vitamin D supplementation may not be helpful in the clinical management of patients with HF.
摘要：
■对心力衰竭（HF）患者补充维生素D效果的系统评估。
■在国家医学图书馆进行了搜索，WebofScience,科克伦图书馆,谷歌学者，中国国家知识基础设施，和万方数据库。我们使用ReviewManager5.4软件分析数据。所有这些都是从最早的记录到2023年3月。结果指标分析左心室射血分数（LVEF），左心室舒张末期内径（LVEDD），B型脑钠肽（BNP）水平和25-羟基维生素D（25（OH）D）水平。
■纳入了10项1099名患者的研究。LVEF（均差（MD）=0.74，95%CI：-0.29至1.76，p=0.41），LVEDD（MD=-0.59，95%CI：-1.83至0.66，p=0.25），BNP（MD=-0.08，95%CI：-0.24至0.08，p=0.34），25（OH）D（MD=0.41，95％CI：-0.28至1.11，p=0.25）没有统计学意义。LVEF的结果没有异质性，LVEDD和BNP指标。
■补充维生素D可能对HF患者的临床治疗没有帮助。
■在国家医学图书馆进行了搜索，WebofScience,科克伦图书馆,谷歌学者，中国国家知识基础设施，和万方数据库。我们使用ReviewManager5.4软件分析数据。所有这些都是从最早的记录到2023年3月。结果指标分析左心室射血分数（LVEF），左心室舒张末期内径（LVEDD），B型脑钠肽（BNP）水平和25-羟基维生素D（25（OH）D）水平。
■纳入了10项1099名患者的研究。LVEF（均差（MD）=0.74，95%CI：-0.29至1.76，p=0.41），LVEDD（MD=-0.59，95%CI：-1.83至0.66，p=0.25），BNP（MD=-0.08，95%CI：-0.24至0.08，p=0.34），25（OH）D（MD=0.41，95％CI：-0.28至1.11，p=0.25）没有统计学意义。LVEF的结果没有异质性，LVEDD和BNP指标。
■补充维生素D可能对HF患者的临床治疗没有帮助。
