PDF(Pubmed)
Abstract：
Mitral annular disjunction (MAD) is a structural abnormality defined by a distinct separation of the mitral valve annulus-left atrial wall continuum and the basal aspect of the posterolateral left ventricle. This anomaly is often observed in patients with myxomatous mitral valve prolapse. Importantly, MAD has been strongly associated with serious ventricular arrhythmias and predisposes to sudden cardiac death. Therefore, we have to emphasize the need to diagnose this morphologic and functional abnormality in routine practice in order to facilitate optimal mitral valve repair and minimize patient risks. Nevertheless, clinical knowledge regarding MAD still remains limited. In the present review, we aim to shed light on several aspects of MAD, including distinct anatomical and pathophysiological characteristics, imaging modalities, association with ventricular arrhythmias, and current methods of treatment.
摘要：
二尖瓣环分离（MAD）是一种结构异常，由二尖瓣环-左心房壁连续体和左心室后外侧基底的明显分离定义。这种异常通常在粘液瘤样二尖瓣脱垂的患者中观察到。重要的是,MAD与严重的室性心律失常密切相关，并容易导致心源性猝死。因此,我们必须强调需要在常规实践中诊断这种形态和功能异常,以促进最佳的二尖瓣修复并将患者风险降至最低.然而，关于MAD的临床知识仍然有限.在本次审查中，我们的目标是阐明MAD的几个方面，包括独特的解剖和病理生理特征，成像模式，与室性心律失常有关，以及目前的治疗方法。
