Mesh : Animals Rats Glucose / metabolism Transforming Growth Factor beta1 / metabolism Octamer Transcription Factor-3 / metabolism genetics MAP Kinase Signaling System / drug effects Cell Cycle Checkpoints Multipotent Stem Cells / metabolism cytology Bone Marrow Cells / metabolism cytology Adult Stem Cells / metabolism cytology

来  源:   DOI:10.1111/1440-1681.13908

Abstract:
M. Luo , Z. Liu , H. Hao , T. Lu , M. Chen , M. Lei , C.M. Verfaillie , and Z. Liu , \"High Glucose Facilitates Cell Cycle Arrest of Rat Bone Marrow Multipotent Adult Progenitor Cells through Transforming Growth Factor-β1 and Extracellular Signal-Regulated Kinase 1/2 Signalling without Changing Oct4 Expression,\" Clinical and Experimental Pharmacology and Physiology 39, no. 10 (2012): 843-851. https://doi.org/10.1111/j.1440-1681.2012.05747.x This Expression of Concern is for the above article, published online on 14 July 2012, in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Yang Yang, and the Publisher, John Wiley & Sons Australia, Ltd. The Expression of Concern has been agreed due to concerns raised by a third party after publication regarding the similarity of certain blots in Figures 2 and 3 and the underlying data that they represent. The authors did not respond to multiple requests for the original data. The journal is issuing this Expression of Concern because the concerns regarding the integrity of the data and the results presented cannot be resolved.
摘要:
罗先生,Z.Liu,H.Hao,T.Lu,M.陈,M.雷,C.M.Verfaillie,Z.Liu,高糖通过转化生长因子β1和细胞外信号调节激酶1/2信号传导促进大鼠骨髓多能成体祖细胞细胞周期阻滞,而不改变Oct4的表达,“临床和实验药理学和生理学”第39期。10(2012):843-851。https://doi.org/10.1111/j.1440-1681.2012.05747.x此关注表达是针对上述文章,2012年7月14日在线出版,Wiley在线图书馆(wileyonlinelibrary.com),并由杂志总编辑之间的协议发行,杨阳,和出版商,约翰威利父子澳大利亚,由于第三方在发布后就图2和图3中某些印迹的相似性及其所代表的基础数据提出的担忧,已同意表达关注。作者没有回应原始数据的多个请求。该期刊发布此关注表达,因为有关数据完整性和所呈现结果的担忧无法解决。
公众号