Abstract:
Medication-related osteonecrosis of the jaw (MRONJ) is a serious condition associated with the use of antiresorptive and antiangiogenic medications. Despite extensive research, the pathophysiology of MRONJ remains poorly understood. Bibliometric analysis provides insights into the academic impact of research, helping identify influential works and emerging trends in this field. This study employed a bibliometric analysis of MRONJ publications indexed in Web of Science from 2003 to 2023. The analysis included English-language articles and utilized the VOSviewer, R Studio Bibliometrix package, and Graphpad to evaluate citation counts, publication trends, and collaboration patterns. This study unveils the current situation of the MRONJ research, addressing well-recognized safety issues of antiresorptive and antiangiogenic agents. Our findings may suggest that the overall trend of the MRONJ research continues to evolve and is not likely to reach its peak or plateau yet. We believe that our work will help to identify gaps in the literature and future research directions, contributing to a better understanding of MRONJ management.
摘要:
与药物相关的颌骨坏死(MRONJ)是与使用抗吸收和抗血管生成药物有关的严重疾病。尽管进行了广泛的研究,MRONJ的病理生理学仍然知之甚少。文献计量分析提供了对研究学术影响的见解,帮助识别该领域有影响力的作品和新兴趋势。这项研究采用了2003年至2023年在WebofScience中索引的MRONJ出版物的文献计量分析。分析包括英语文章,并利用VOSviewer,RStudioBibliometrix软件包,和Graphpad来评估引文计数,出版趋势,和协作模式。本研究揭示了MRONJ研究的现状,解决公认的抗吸收和抗血管生成剂的安全性问题。我们的发现可能表明,MRONJ研究的总体趋势仍在继续发展,并且不太可能达到顶峰或高原。我们相信,我们的工作将有助于找出文献中的差距和未来的研究方向,有助于更好地理解MRONJ管理。