关键词: Canada First Nations Inuit Lung Metis cancer

Mesh : Humans Lung Neoplasms / ethnology mortality Canada / epidemiology Inuit / statistics & numerical data Incidence Indians, North American / statistics & numerical data Arctic Regions / epidemiology

来  源:   DOI:10.1080/22423982.2024.2381879   PDF(Pubmed)

Abstract:
Lung cancer is one of the most commonly diagnosed cancers in Canada and a leading cause of cancer mortality. Lung cancer also affects First Nations, Inuit and Métis peoples significantly in Canada, which deserves further investigation as there is a literature gap on this topic. We sought to develop a deeper understanding of lung cancer diagnosis, incidence, mortality, and survival in First Nations, Inuit, and Métis peoples in Canada. A systematic search was conducted in bibliographic databases to identify relevant studies published between January 2000 and March 2023. Articles were screened and assessed for relevance using the Population/ Concept/ Context (PCC) framework. A total of 22 articles were included in the final analysis, of which 13 were Inuit-specific, 7 were First Nations-specific, and 2 were Métis-specific. The literature suggests that comparative incidence, mortality, and relative risk of lung cancer is higher and survival is poorer in First Nations, Inuit and Métis peoples. Lung cancer also has varying impact on these population depending on sex, age, location and other factors. This review illustrates that more comprehensive quantitative and qualitative lung cancer research is essential to further identify the structural causes for the high incidence of the disease.
摘要:
肺癌是加拿大最常见的癌症之一,也是癌症死亡的主要原因。肺癌也会影响原住民,因纽特人和梅蒂斯人在加拿大显着,这值得进一步调查,因为在这个话题上存在文献空白。我们寻求对肺癌诊断有更深入的了解,发病率,死亡率,在第一民族中生存,因纽特人,和加拿大的梅蒂斯人。在书目数据库中进行了系统的搜索,以确定2000年1月至2023年3月之间发表的相关研究。使用人口/概念/背景(PCC)框架对文章进行了筛选和相关性评估。共有22篇文章被纳入最终分析,其中13个是因纽特人特有的,7是针对第一民族的,2个是梅蒂斯特有的。文献表明,比较发病率,死亡率,原住民患肺癌的相对风险更高,生存率更差,因纽特人和梅蒂斯人。肺癌对这些人群也有不同的影响,取决于性别,年龄,位置和其他因素。这篇综述表明,更全面的定量和定性研究对于进一步确定肺癌高发的结构性原因至关重要。
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