Abstract：
Inulin, a naturally occurring polysaccharide derived from plants such as chicory root, has emerged as a significant ingredient in pharmaceutical sciences due to its diverse therapeutic and functional properties. This review explores the multifaceted applications of inulin, focusing on its chemical structure, sources, and mechanisms of action. Inulin\'s role as a prebiotic is highlighted, with particular emphasis on its ability to modulate gut microbiota, enhance gut health, and improve metabolic processes. The review also delves into the therapeutic applications of inulin, including its potential in managing metabolic health issues such as diabetes and lipid metabolism, as well as its immune-modulating properties and benefits in gastrointestinal health. Furthermore, the article examines the incorporation of inulin in drug formulation and delivery systems, discussing its use as a stabilizing agent and its impact on enhancing drug bioavailability. Innovative inulin-based delivery systems, such as nanoparticles and hydrogels, are explored for their potential in controlled release formulations. The efficacy of inulin is supported by a review of clinical studies, underscoring its benefits in managing conditions like diabetes, cardiovascular health, and gastrointestinal disorders. Safety profiles, regulatory aspects, and potential side effects are also addressed. This comprehensive review concludes with insights into future research directions and the challenges associated with the application of inulin in pharmaceutical sciences.
摘要：
菊粉,一种来自菊苣根等植物的天然多糖，由于其多样化的治疗和功能特性，已成为药物科学中的重要成分。这篇综述探讨了菊粉的多方面应用，关注它的化学结构，来源,和行动机制。菊粉作为益生元的作用被强调，特别强调其调节肠道微生物群的能力，增强肠道健康，并改善代谢过程。该综述还深入研究了菊粉的治疗应用，包括它在管理代谢健康问题如糖尿病和脂质代谢方面的潜力，以及它的免疫调节特性和对胃肠道健康的好处。此外，本文研究了菊粉在药物制剂和给药系统中的掺入，讨论其作为稳定剂的用途及其对提高药物生物利用度的影响。创新的基于菊粉的输送系统，如纳米粒子和水凝胶，探索了它们在控释制剂中的潜力。菊粉的功效得到了临床研究综述的支持，强调它在管理糖尿病等疾病方面的好处，心血管健康,和胃肠道疾病。安全概况,监管方面，和潜在的副作用也得到了解决。这篇全面的综述总结了对未来研究方向的见解以及与菊粉在药物科学中的应用相关的挑战。
