Abstract：
Despite recent advances in the management and therapeutic of cancer, the treatment of the disease is limited by its high cost and severe side effects. In this scenario, there is an unmet need to identify novel treatment alternatives for this dreaded disease. Recently there is growing evidence that parasites may cause anticancer effects because of a negative correlation between parasitic infections and tumour growth despite some parasites that are known to exhibit pro-carcinogenic effects. It has been observed that parasites exert an anticancer effect either by activating the host\'s immune response or by secreting certain molecules that exhibit anticancer potential. The activation of the immune response by these parasitic organisms results in the inhibition of some of the hallmarks of cancer such as tumour proliferation, angiogenesis, and metastasis. This review summarizes the current advances as well as the mechanisms underlying the possible implications of this diverse group of organisms as anticancer agents.
摘要：
尽管最近在癌症的管理和治疗方面取得了进展，该疾病的治疗受到其高成本和严重副作用的限制。在这种情况下，有一个未满足的需要，以确定新的治疗替代方案，这种可怕的疾病。最近，越来越多的证据表明，尽管已知某些寄生虫表现出致癌作用，但由于寄生虫感染与肿瘤生长之间存在负相关，因此寄生虫可能会引起抗癌作用。已经观察到寄生虫通过激活宿主的免疫应答或通过分泌某些表现出抗癌潜力的分子来发挥抗癌作用。这些寄生生物激活的免疫反应导致抑制癌症的一些标志，如肿瘤增殖，血管生成,和转移。这篇综述总结了当前的进展以及这种不同种类的生物作为抗癌剂可能影响的潜在机制。
