Abstract：
Xerosis is highly prevalent in the population aged over 50 years and substantially impacts quality of life due to the associated stigma, related pruritus, and potential sequelae. We propose that the term mature xerosis be used for subjects over 50 who suffer from age-related xerosis and replace senile xerosis to describe the phenomenon. The etiology of xerosis depends on genetic and environmental factors that affect stratum corneum hydration and skin barrier function. Skincare to restore barrier function is essential in xerosis treatment and is relevant for maintaining and preventing its progression. Many moisturizers and cleansers are available for xerosis; however, they are underutilized by patients with mature xerosis. A panel of eight global dermatologists reviewed the unique aspects of xerosis in mature skin and discussed the specific needs, relevance, and considerations for skincare selection to prevent, treat, and maintain skin with mature xerosis. The panel selected five statements based on evidence from a literature review and the panel\'s clinical experience to provide clinical considerations and recommendations for dermatologists and other healthcare providers treating patients with mature xerosis. Increased recognition of the burden of xerosis in mature skin is warranted. Gentle cleansers and barrier-restoring ceramide-containing moisturizers are essential to xerosis management, reducing signs and symptoms of xerosis, including associated pruritus.
摘要：
干燥症在50岁以上的人群中非常普遍，由于相关的耻辱，严重影响生活质量。相关瘙痒，和潜在的后遗症。我们建议将术语“成熟干燥症”用于50岁以上患有与年龄相关的干燥症的受试者，并代替老年干燥症来描述这种现象。干燥病的病因取决于影响角质层水合和皮肤屏障功能的遗传和环境因素。恢复屏障功能的护肤在干燥症治疗中是必不可少的，并且与维持和预防其进展有关。许多保湿剂和清洁剂可用于干燥病；然而，成熟干燥症患者对它们的利用不足。由八位全球皮肤科医生组成的小组回顾了干燥症在成熟皮肤中的独特方面，并讨论了具体需求，相关性，和护肤品选择的注意事项，以防止，请客,并保持皮肤成熟干燥。小组根据文献综述的证据和小组的临床经验选择了五个陈述，为皮肤科医生和其他医疗保健提供者治疗成熟干燥症患者提供临床考虑和建议。有必要增加对成熟皮肤干燥病负担的认识。温和的清洁剂和屏障恢复含神经酰胺的保湿剂对干燥管理至关重要，减少干燥症的体征和症状，包括相关的瘙痒。
