Abstract：
UNASSIGNED: Trauma exposure (TE) and cognitive flexibility (CF) are risk factors for self-injurious thoughts and behaviors (SITBs). However, it is unknown whether these risk factors contribute to mechanisms associated with distinct categories of SITBs. The current study examined the potential moderating role of TE in the relationships between CF and multiple SITBs, including active suicidal ideation (SI), passive SI, non-suicidal self-injury (NSSI), and history of suicide attempt (SA), among pre-adolescent children.
UNASSIGNED: A total of 11,326 children from the Adolescent Brain Cognitive Development study were included in the present study. SITBs and TE were measured by the Kiddy Schedule for Affective Disorder and Schizophrenia (KSADS). CF was measured using the NIH Cognitive Toolbox.
UNASSIGNED: Cumulative TE moderated the relationship of CF to active SI. Higher CF was associated with lower odds of current SI in children with a single lifetime TE, but not in children without trauma or with two or more TE. As a main effect, two or more TE predicted higher odds of active SI, passive SI, and lifetime SA, but not NSSI. Higher CF was associated with lower odds of passive SI, with effects not moderated by trauma exposure.
UNASSIGNED: The current results clarify previously inconsistent findings about the relationship of CF to SI by identifying cumulative TE as a moderator. CF served as a protective factor against SI, but only in children with a single lifetime trauma. Implications for screening and treatment targets of children at risk for distinct categories of SITBs are discussed.
UNASSIGNED: A total of 11,326 children from the Adolescent Brain Cognitive Development study were included in the present study. SITBs and TE were measured by the Kiddy Schedule for Affective Disorder and Schizophrenia (KSADS). CF was measured using the NIH Cognitive Toolbox.
UNASSIGNED: Cumulative TE moderated the relationship of CF to active SI. Higher CF was associated with lower odds of current SI in children with a single lifetime TE, but not in children without trauma or with two or more TE. As a main effect, two or more TE predicted higher odds of active SI, passive SI, and lifetime SA, but not NSSI. Higher CF was associated with lower odds of passive SI, with effects not moderated by trauma exposure.
UNASSIGNED: The current results clarify previously inconsistent findings about the relationship of CF to SI by identifying cumulative TE as a moderator. CF served as a protective factor against SI, but only in children with a single lifetime trauma. Implications for screening and treatment targets of children at risk for distinct categories of SITBs are discussed.
摘要：
■创伤暴露（TE）和认知灵活性（CF）是自我伤害思想和行为（SITB）的危险因素。然而,目前尚不清楚这些危险因素是否与不同类别的SITB相关机制有关.当前的研究检查了TE在CF与多个SITB之间的关系中的潜在调节作用，包括主动自杀意念(SI)，被动SI，非自杀性自伤（NSSI），和自杀未遂史（SA），在青春期前的孩子中。
■共有11,326名青少年大脑认知发育研究的儿童被纳入本研究。通过情感障碍和精神分裂症的肾脏时间表（KSADS）测量SITB和TE。使用NIH认知工具箱测量CF。
■累积TE缓和了CF与活跃SI的关系。在单生命周期TE的儿童中，较高的CF与较低的当前SI几率相关，但不适用于无创伤或有两个或两个以上TE的儿童。作为主要影响，两个或两个以上的TE预测活跃SI的几率更高，被动SI，和终身SA，但不是NSSI.较高的CF与较低的被动SI几率相关，创伤暴露不能缓解的影响。
■当前的结果通过将累积TE识别为主持人，澄清了以前关于CF与SI关系的不一致发现。CF作为抗SI的保护因素，但仅限于一生遭受创伤的儿童。讨论了有不同类别SITB风险的儿童的筛查和治疗目标的含义。
■共有11,326名青少年大脑认知发育研究的儿童被纳入本研究。通过情感障碍和精神分裂症的肾脏时间表（KSADS）测量SITB和TE。使用NIH认知工具箱测量CF。
■累积TE缓和了CF与活跃SI的关系。在单生命周期TE的儿童中，较高的CF与较低的当前SI几率相关，但不适用于无创伤或有两个或两个以上TE的儿童。作为主要影响，两个或两个以上的TE预测活跃SI的几率更高，被动SI，和终身SA，但不是NSSI.较高的CF与较低的被动SI几率相关，创伤暴露不能缓解的影响。
■当前的结果通过将累积TE识别为主持人，澄清了以前关于CF与SI关系的不一致发现。CF作为抗SI的保护因素，但仅限于一生遭受创伤的儿童。讨论了有不同类别SITB风险的儿童的筛查和治疗目标的含义。
