关键词: cystic fibrosis exacerbations pollution

来  源:   DOI:10.1515/reveh-2024-0068

Abstract:
Cystic fibrosis is the most common autosomal recessive disease in the Caucasian race. Its course is chronic and progressive, with pulmonary involvement being associated with greater morbidity and mortality. One of the factors most related to worse prognosis in these patients is respiratory exacerbations. Although limited, there is evidence demonstrating that increased exposure to environmental pollution, both acute and chronic, is associated with an increase in these exacerbations. It is crucial to fully understand this relationship in order to attempt to improve the respiratory health of these patients. That is why the available evidence is reviewed and measures are established to reduce exposure to pollutants.
摘要:
囊性纤维化是高加索种族中最常见的常染色体隐性疾病。它的过程是慢性和进行性的,肺部受累与更高的发病率和死亡率相关。与这些患者预后较差最相关的因素之一是呼吸恶化。虽然有限,有证据表明,暴露于环境污染的增加,急性和慢性,与这些恶化的增加有关。为了试图改善这些患者的呼吸健康,充分理解这种关系至关重要。这就是为什么要审查现有证据并制定措施以减少对污染物的暴露。
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