关键词: clinical research general dermatology laser medical dermatology surgery treatment response

来  源:   DOI:10.1016/j.jdin.2024.04.005   PDF(Pubmed)

Abstract:
UNASSIGNED: Hidradenitis supprativa is a chronic inflammatory skin disease that can respond to treatment with laser hair removal.
UNASSIGNED: To assess alexandrite laser hair removal laser as a treatment for hidradenitis suppurativa as measured by the Hidradenitis Supprativa Clinical Response.
UNASSIGNED: We conducted a prospective, randomized, controlled study in adult patients with hidradenitis supprativa. Participants underwent a series of 4 monthly laser treatments to 1 side of the body, with the contralateral side serving as a control. The primary outcome was Hidradenitis Supprativa Clinical Response at week 24, 8 weeks after the final laser treatment.
UNASSIGNED: The percent improvement across treated sites after 4 treatments was 72.73% axillary, 70% inguinal, and 100% inframammary. Across all body regions, Hidradenitis Supprativa Clinical Response was significantly higher for the sites treated with the alexandrite laser compared to the contralateral controls: 75% vs 33.33% (P = .0046, 95% CI: [0.16, 1]).
UNASSIGNED: The limitations of this study include a small sample size from which the data was collected.
UNASSIGNED: The 775-nm alexandrite laser is a safe and effective treatment for hidradenitis supprativa at various anatomic sites in both resolving preexisting lesions and preventing new eruptions.
摘要:
汗腺炎是一种慢性炎症性皮肤病,可对激光脱毛治疗产生反应。
评估紫绿宝石激光脱毛激光治疗化脓性汗腺炎的临床反应。
我们进行了前瞻性,随机化,成人汗腺炎患者的对照研究。参与者对身体的一侧进行了一系列4个月的激光治疗,对侧作为对照。主要结果是最终激光治疗后第24周,第8周的汗腺炎临床反应。
4次治疗后,治疗部位的改善百分比为72.73%,70%腹股沟,和100%的乳房下。在所有身体部位,与对侧对照相比,使用翠绿宝石激光治疗的部位的临床反应明显更高:75%vs33.33%(P=.0046,95%CI:[0.16,1])。
这项研究的局限性包括收集数据的样本量很小。
775-nm翠绿宝石激光是一种安全有效的治疗方法,可以在各种解剖部位解决先前存在的病变并防止新的喷发。
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