PDF(Pubmed)
Abstract：
UNASSIGNED: Applying autologous growth factors and diode laser in periodontal therapy enhances fibroblast-mediated new attachment and osteoblastic differentiation. Hence, this study compared and evaluated the effectiveness of concentrated growth factor (CGF) alone and with diode laser application in managing intrabony periodontal defects.
UNASSIGNED: Ten patients with stage III periodontitis were included in this study. All the patients underwent an open flap debridement (OFD) procedure followed by CGF membrane placement in the intrabony defect in site A, whereas, in site B, after OFD, all the patients underwent diode laser irradiation before CGF membrane placement. Plaque and gingival bleeding index (PI & GBI), PPD, and clinical attachment level (CAL) were evaluated at baseline and 3 and 6 months later. Bone fill (BF), BF%, bone crest changes (BCC), and BCC% were assessed radiographically at six months postoperatively.
UNASSIGNED: Significant reductions in PI and GBI scores, probing pocket depth (PPD), and CAL gain were observed at both sites 3 and 6 months from baseline. A significant reduction in PPD and CAL gain was noted between sites, which were higher in site B than in site A with a mean difference of 0.70±0.05 mm and 1.30±0.18 mm, 0.90±1.89 mm at 3 and 6 months, respectively. Radiographic measurement showed better BF, BF%, BCC, and BCC% at both sites at six months, which were higher at site B than at site A but statistically insignificant.
UNASSIGNED: The combination of CGF and diode laser application has demonstrated successful and promising results in terms of regeneration, improving the clinical and radiographic parameters.
UNASSIGNED: Ten patients with stage III periodontitis were included in this study. All the patients underwent an open flap debridement (OFD) procedure followed by CGF membrane placement in the intrabony defect in site A, whereas, in site B, after OFD, all the patients underwent diode laser irradiation before CGF membrane placement. Plaque and gingival bleeding index (PI & GBI), PPD, and clinical attachment level (CAL) were evaluated at baseline and 3 and 6 months later. Bone fill (BF), BF%, bone crest changes (BCC), and BCC% were assessed radiographically at six months postoperatively.
UNASSIGNED: Significant reductions in PI and GBI scores, probing pocket depth (PPD), and CAL gain were observed at both sites 3 and 6 months from baseline. A significant reduction in PPD and CAL gain was noted between sites, which were higher in site B than in site A with a mean difference of 0.70±0.05 mm and 1.30±0.18 mm, 0.90±1.89 mm at 3 and 6 months, respectively. Radiographic measurement showed better BF, BF%, BCC, and BCC% at both sites at six months, which were higher at site B than at site A but statistically insignificant.
UNASSIGNED: The combination of CGF and diode laser application has demonstrated successful and promising results in terms of regeneration, improving the clinical and radiographic parameters.
摘要：
■在牙周治疗中应用自体生长因子和二极管激光可增强成纤维细胞介导的新附着和成骨细胞分化。因此，这项研究比较并评估了单独使用浓缩生长因子（CGF）和二极管激光治疗牙内牙周缺损的有效性。
■本研究纳入了10例III期牙周炎患者。所有患者均接受了开放皮瓣清创（OFD）手术，然后将CGF膜放置在部位A的骨内缺损中，然而,在站点B中，OFD后，所有患者在CGF膜置入前均接受二极管激光照射.菌斑和牙龈出血指数（PI和GBI），PPD,在基线和3个月和6个月后评估临床依恋水平(CAL).骨填充（BF），BF%,骨冠变化（BCC），和BCC％在术后6个月进行影像学评估。
■PI和GBI分数显著降低，探测袋深度（PPD），在距基线3个月和6个月的位置观察到CAL增加。站点之间的PPD和CAL增益显着降低，B部位高于A部位，平均差为0.70±0.05mm和1.30±0.18mm，3个月和6个月时为0.90±1.89mm，分别。射线照相测量显示更好的BF，BF%,密件抄送,六个月时，两个地点的BCC%，B部位高于A部位，但无统计学意义。
■CGF和二极管激光器应用的结合在再生方面已经证明了成功和有希望的结果，改善临床和影像学参数。
■本研究纳入了10例III期牙周炎患者。所有患者均接受了开放皮瓣清创（OFD）手术，然后将CGF膜放置在部位A的骨内缺损中，然而,在站点B中，OFD后，所有患者在CGF膜置入前均接受二极管激光照射.菌斑和牙龈出血指数（PI和GBI），PPD,在基线和3个月和6个月后评估临床依恋水平(CAL).骨填充（BF），BF%,骨冠变化（BCC），和BCC％在术后6个月进行影像学评估。
■PI和GBI分数显著降低，探测袋深度（PPD），在距基线3个月和6个月的位置观察到CAL增加。站点之间的PPD和CAL增益显着降低，B部位高于A部位，平均差为0.70±0.05mm和1.30±0.18mm，3个月和6个月时为0.90±1.89mm，分别。射线照相测量显示更好的BF，BF%,密件抄送,六个月时，两个地点的BCC%，B部位高于A部位，但无统计学意义。
■CGF和二极管激光器应用的结合在再生方面已经证明了成功和有希望的结果，改善临床和影像学参数。
