PDF(Pubmed)
Abstract：
UNASSIGNED: Acute appendicitis (AA) is the predominant condition responsible for acute abdominal pain across all age demographics. The purpose of this research is to determine if the hemoglobin, albumin, lymphocyte, and platelet (HALP) and modified HALP (m-HALP) scores differ between complicated and uncomplicated appendicitis in patients diagnosed with AA who have applied to the emergency department (ED). Additionally, this study aims to investigate whether HALP and m-HALP scores are superior to other biomarkers.
UNASSIGNED: The retrospective analysis included adult patients, aged eighteen or older, who were diagnosed with AA, and sought treatment at the ED of a tertiary hospital. Patients were divided into two groups: complicated appendicitis (CA) and uncomplicated appendicitis (UCA). The cut-off in diagnostic value measurements was determined using the receiver operating characteristic analysis.
UNASSIGNED: A total of 436 patients (CA: 126, UCA: 310) were included. Neutrophil-to-lymphocyte ratio (NLR), neutrophil-to-albumin ratio, systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and pan-immune inflammation value (PIV) were found to have acceptable diagnostic power in CA detection (area under the curve [AUC]: 0.735-0.783). In detecting UCA, HALP and m-HALP were of fair diagnostic power (AUC: 0.64, 0.68, respectively).
UNASSIGNED: In this study, we found that although PIV, SIRI, SII, and NLR had acceptable diagnostic values in distinguishing CA and UCA, HALP and m-HALP had fair diagnostic values.
UNASSIGNED: The retrospective analysis included adult patients, aged eighteen or older, who were diagnosed with AA, and sought treatment at the ED of a tertiary hospital. Patients were divided into two groups: complicated appendicitis (CA) and uncomplicated appendicitis (UCA). The cut-off in diagnostic value measurements was determined using the receiver operating characteristic analysis.
UNASSIGNED: A total of 436 patients (CA: 126, UCA: 310) were included. Neutrophil-to-lymphocyte ratio (NLR), neutrophil-to-albumin ratio, systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and pan-immune inflammation value (PIV) were found to have acceptable diagnostic power in CA detection (area under the curve [AUC]: 0.735-0.783). In detecting UCA, HALP and m-HALP were of fair diagnostic power (AUC: 0.64, 0.68, respectively).
UNASSIGNED: In this study, we found that although PIV, SIRI, SII, and NLR had acceptable diagnostic values in distinguishing CA and UCA, HALP and m-HALP had fair diagnostic values.
摘要：
■急性阑尾炎（AA）是所有年龄人口统计学中导致急性腹痛的主要疾病。这项研究的目的是确定血红蛋白，白蛋白,淋巴细胞，在诊断为AA且已申请急诊科（ED）的患者中，复杂和非复杂阑尾炎的血小板（HALP）和改良HALP（m-HALP）评分不同。此外,本研究旨在调查HALP和m-HALP评分是否优于其他生物标志物.
■回顾性分析包括成年患者，18岁或以上，被诊断为AA，并在三级医院的急诊室寻求治疗。患者分为两组：复杂性阑尾炎（CA）和非复杂性阑尾炎（UCA）。使用接收器工作特性分析确定诊断值测量的截止值。
■共纳入436例患者(CA:126,UCA:310)。中性粒细胞与淋巴细胞比率（NLR），中性粒细胞与白蛋白的比率，全身免疫炎症指数（SII），全身炎症反应指数（SIRI），发现泛免疫炎症值(PIV)在CA检测中具有可接受的诊断能力(曲线下面积[AUC]:0.735-0.783)。在检测UCA时，HALP和m-HALP具有相当的诊断能力(AUC分别为0.64、0.68)。
■在这项研究中，我们发现虽然PIV,SIRI,SII,NLR在区分CA和UCA方面具有可接受的诊断价值，HALP和m-HALP具有良好的诊断价值。
■回顾性分析包括成年患者，18岁或以上，被诊断为AA，并在三级医院的急诊室寻求治疗。患者分为两组：复杂性阑尾炎（CA）和非复杂性阑尾炎（UCA）。使用接收器工作特性分析确定诊断值测量的截止值。
■共纳入436例患者(CA:126,UCA:310)。中性粒细胞与淋巴细胞比率（NLR），中性粒细胞与白蛋白的比率，全身免疫炎症指数（SII），全身炎症反应指数（SIRI），发现泛免疫炎症值(PIV)在CA检测中具有可接受的诊断能力(曲线下面积[AUC]:0.735-0.783)。在检测UCA时，HALP和m-HALP具有相当的诊断能力(AUC分别为0.64、0.68)。
■在这项研究中，我们发现虽然PIV,SIRI,SII,NLR在区分CA和UCA方面具有可接受的诊断价值，HALP和m-HALP具有良好的诊断价值。
