PDF(Pubmed)
Abstract：
Amitraz poisoning is being increasingly seen in clinical practice, presenting physicians with challenges due to its rapidity of onset of severe clinical features, its similarity with organophosphate poisoning and the absence of specific antidotes. Early initiation and appropriate treatment are vital for favourable outcomes. Our case report is of a 40-year-old male who presented to us with grave clinical features following deliberate ingestion of Amitraz in a suicidal attempt. On arrival, he had bradycardia, hypotension, respiratory depression, and altered sensorium. Immediate administration of atropine stabilised his vital signs. Laboratory investigations revealed uncommon electrolyte imbalances, which were promptly corrected. The patient received supportive care in the intensive care unit (ICU), regained consciousness within three days, and was discharged after a week of hospitalisation. Despite the rapid onset and severity of symptoms caused by Amitraz poisoning, early intervention and supportive care can lead to a full recovery. This case underscores the importance of promptly recognising Amitraz poisoning and initiating treatment, its similarity with organophosphate poisoning and the role of atropine. Further research is needed to establish comprehensive management guidelines for tackling this emerging poisoning hazard.
摘要：
Amitraz中毒在临床实践中越来越多，由于其严重临床特征的快速发作，给医生带来了挑战，它与有机磷中毒相似，没有特定的解毒剂。早期开始和适当的治疗对于有利的结果至关重要。我们的病例报告是一名40岁的男性，他在自杀企图中故意摄入Amitraz后向我们展示了严重的临床特征。抵达后,他有心动过缓,低血压,呼吸抑制,和改变的感官。立即服用阿托品稳定了他的生命体征。实验室调查显示不常见的电解质失衡，迅速纠正。患者在重症监护病房（ICU）接受支持性护理，三天内恢复了意识,住院一周后出院。尽管由Amitraz中毒引起的症状起病迅速且严重，早期干预和支持治疗可导致完全康复.此案强调了迅速认识到Amitraz中毒并开始治疗的重要性，它与有机磷中毒和阿托品的作用相似。需要进一步研究以建立应对这种新出现的中毒危险的综合管理指南。
