PDF(Pubmed)
Abstract：
UNASSIGNED: Through preoperative localization, surgeons can easily locate ground glass nodules (GGNs) and effectively control the extent of resection. Therefore, it is necessary to choose an appropriate puncture positioning method. The purpose of this study was to evaluate the effectiveness and safety of medical glue and positioning hooks in the preoperative positioning of GGNs and to provide a reference for clinical selection.
UNASSIGNED: From March 30, 2020 to June 13, 2022, a total of 859 patients with a CT diagnosis of GGNs requiring surgical resection were included in our study at the hospital. Among them, 21 patients who either opted out or could not undergo preoperative localization for various reasons were excluded. Additionally, 475 patients who underwent preoperative localization using medical glue and 363 patients who underwent preoperative localization through positioning hooks were also excluded. We conducted statistical analyses on the baseline data, success rates, complications, and pathological results of the remaining patients. The success rates, complication rates, and pathological results were compared between the two groups-those who received medical glue localization and those who received positioning hook localization.
UNASSIGNED: There was no statistically significant difference between the two groups of patients in terms of age, body mass index, smoking history, location of the nodule, distance of the nodule from the pleura, or postoperative pathological results (P > 0.05). The success rate of medical glue and positioning hooks was 100%. The complication rates of medical glue and positioning hooks during single nodule positioning were 39.18% and 23.18%, respectively, which were significantly different (p < 0.001); the complication rates during multiple nodule positioning were 49.15% and 49.18%, respectively, with no statistically significant differences (p > 0.05). In addition, the method of positioning and the clinical characteristics of the patients were not found to be independent risk factors for the occurrence of complications. The detection rate of pulmonary nodules also showed some positive correlation with the spread of COVID-19 during the 2020-2022 period when COVID-19 was prevalent.
UNASSIGNED: When positioning a single node, the safety of positioning hooks is greater than when positioning multiple nodes, the safety of medical glue and positioning hooks is comparable, and the appropriate positioning method should be chosen according to the individual situation of the patient.
UNASSIGNED: From March 30, 2020 to June 13, 2022, a total of 859 patients with a CT diagnosis of GGNs requiring surgical resection were included in our study at the hospital. Among them, 21 patients who either opted out or could not undergo preoperative localization for various reasons were excluded. Additionally, 475 patients who underwent preoperative localization using medical glue and 363 patients who underwent preoperative localization through positioning hooks were also excluded. We conducted statistical analyses on the baseline data, success rates, complications, and pathological results of the remaining patients. The success rates, complication rates, and pathological results were compared between the two groups-those who received medical glue localization and those who received positioning hook localization.
UNASSIGNED: There was no statistically significant difference between the two groups of patients in terms of age, body mass index, smoking history, location of the nodule, distance of the nodule from the pleura, or postoperative pathological results (P > 0.05). The success rate of medical glue and positioning hooks was 100%. The complication rates of medical glue and positioning hooks during single nodule positioning were 39.18% and 23.18%, respectively, which were significantly different (p < 0.001); the complication rates during multiple nodule positioning were 49.15% and 49.18%, respectively, with no statistically significant differences (p > 0.05). In addition, the method of positioning and the clinical characteristics of the patients were not found to be independent risk factors for the occurrence of complications. The detection rate of pulmonary nodules also showed some positive correlation with the spread of COVID-19 during the 2020-2022 period when COVID-19 was prevalent.
UNASSIGNED: When positioning a single node, the safety of positioning hooks is greater than when positioning multiple nodes, the safety of medical glue and positioning hooks is comparable, and the appropriate positioning method should be chosen according to the individual situation of the patient.
摘要：
■通过术前定位，外科医生可以轻松定位磨玻璃结节（GGNs）并有效控制切除范围。因此,有必要选择合适的穿刺定位方法。目的评价医用胶和定位钩在GGNs术前定位中的有效性和安全性,为临床选择提供参考。
■从2020年3月30日至2022年6月13日，共有859例CT诊断为需要手术切除的GGNs的患者被纳入我们医院的研究。其中,排除了21例因各种原因选择退出或无法进行术前定位的患者。此外,还排除了475例使用医用胶进行术前定位的患者和363例通过定位钩进行术前定位的患者。我们对基线数据进行了统计分析，成功率,并发症,其余患者的病理结果。成功率,并发症发生率,比较两组的病理结果-接受医用胶定位的患者和接受定位钩定位的患者。
■两组患者在年龄方面无统计学差异，身体质量指数,吸烟史,结节的位置，结节与胸膜的距离，或术后病理结果(P>0.05)。医用胶和定位钩的成功率为100%。单结节定位过程中医用胶和定位钩的并发症发生率分别为39.18%和23.18%,分别,差异有统计学意义（p<0.001）；多结节定位的并发症发生率分别为49.15％和49.18％，分别,差异无统计学意义(p>0.05)。此外,定位方法和患者的临床特征未发现是发生并发症的独立危险因素。在COVID-19流行的2020-2022年期间，肺结节的检出率也与COVID-19的传播呈正相关。
■定位单个节点时，定位钩的安全性大于定位多个节点时，医用胶和定位钩的安全性相当，应根据患者的个体情况选择合适的定位方法。
■从2020年3月30日至2022年6月13日，共有859例CT诊断为需要手术切除的GGNs的患者被纳入我们医院的研究。其中,排除了21例因各种原因选择退出或无法进行术前定位的患者。此外,还排除了475例使用医用胶进行术前定位的患者和363例通过定位钩进行术前定位的患者。我们对基线数据进行了统计分析，成功率,并发症,其余患者的病理结果。成功率,并发症发生率,比较两组的病理结果-接受医用胶定位的患者和接受定位钩定位的患者。
■两组患者在年龄方面无统计学差异，身体质量指数,吸烟史,结节的位置，结节与胸膜的距离，或术后病理结果(P>0.05)。医用胶和定位钩的成功率为100%。单结节定位过程中医用胶和定位钩的并发症发生率分别为39.18%和23.18%,分别,差异有统计学意义（p<0.001）；多结节定位的并发症发生率分别为49.15％和49.18％，分别,差异无统计学意义(p>0.05)。此外,定位方法和患者的临床特征未发现是发生并发症的独立危险因素。在COVID-19流行的2020-2022年期间，肺结节的检出率也与COVID-19的传播呈正相关。
■定位单个节点时，定位钩的安全性大于定位多个节点时，医用胶和定位钩的安全性相当，应根据患者的个体情况选择合适的定位方法。
