关键词: Acute lymphoblastic leukemia Fast microbiology Fungemia Malassezia furfur Unmet need

来  源:   DOI:10.1016/j.mmcr.2024.100657   PDF(Pubmed)

Abstract:
The opportunistic fungus Malassezia furfur (M. furfur) can cause either cutaneous or systemic infections. We report a case of M. furfur fungemia in a 22-year-old male with T-cell Acute Lymphoblastic Leukemia (T-ALL) who developed concomitant Bacillus cereus (B. cereus) septicemia. The fungal infection was diagnosed by microscopic examination and culture-based methods, while automated blood culture systems and molecular approaches failed in identifying the fungus. Despite appropriate therapy, the patient died 18 days after the hospitalization.
摘要:
机会性真菌malasseziafurfur(M.furfur)可引起皮肤或全身感染。我们报告了一例22岁的男性T细胞急性淋巴细胞白血病(T-ALL)并发蜡样芽孢杆菌(B.蜡质)败血症。通过显微镜检查和基于培养的方法诊断真菌感染。而自动化血液培养系统和分子方法未能识别真菌。尽管有适当的治疗,患者在住院18天后死亡.
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