Abstract:
Sickle cell lung disease presents a challenging care paradigm involving acute and chronic lower airway disease, sleep-disordered breathing, pulmonary vascular disease, and modification by environmental factors. Understanding the presentation, pathophysiology, and diagnostic approaches is essential for accurate identification and management. While significant progress has been made, there remains a need for research to develop effective treatments and interventions to decrease disease burden in these children. Additionally, the long-term impact of interventions on cardiopulmonary outcomes is unknown. Collaborative efforts among health care providers, researchers, advocacy groups, and policy makers are crucial to improving the lives of children with SCD.
摘要:
镰状细胞肺疾病提出了一个具有挑战性的护理模式,涉及急性和慢性下气道疾病,睡眠呼吸紊乱,肺血管疾病,和环境因素的改变。理解演示文稿,病理生理学,诊断方法对于准确的识别和管理至关重要。虽然取得了重大进展,仍然需要研究开发有效的治疗方法和干预措施,以减轻这些儿童的疾病负担.此外,干预措施对心肺结局的长期影响尚不清楚.卫生保健提供者之间的合作努力,研究人员,倡导团体,政策制定者对改善SCD儿童的生活至关重要。