Abstract：
Oral mucositis (OM) is a prevalent side effect of chemotherapy that negatively impacts patient quality of life (QoL). Educational guidelines may provide strategies to mitigate these effects.
To evaluate the effectiveness of educational guidelines on the severity of OM and QoL in oncology patients undergoing chemotherapy.
A quasi-experimental study was conducted. Patients (n = 108) were randomly assigned to an intervention group receiving educational guidelines or a control group receiving routine care. Outcomes were assessed at baseline and at one and three months post-intervention. Data were collected using a structured interview including assessments of personal characteristics, clinical data, chemotherapy side effects, OM severity, and QoL.
Baseline QoL scores were comparable between groups. Post-intervention, the intervention group experienced significant improvements in QoL (p ≤ 0.05), while the control group showed a decline. OM severity was significantly reduced in the intervention group compared to the control group at both time points (p ≤ 0.05).
Educational guidelines are an effective intervention for reducing OM severity and improving QoL in oncology patients receiving chemotherapy. Implementation of these guidelines can enhance patient well-being and support optimal treatment outcomes.
To evaluate the effectiveness of educational guidelines on the severity of OM and QoL in oncology patients undergoing chemotherapy.
A quasi-experimental study was conducted. Patients (n = 108) were randomly assigned to an intervention group receiving educational guidelines or a control group receiving routine care. Outcomes were assessed at baseline and at one and three months post-intervention. Data were collected using a structured interview including assessments of personal characteristics, clinical data, chemotherapy side effects, OM severity, and QoL.
Baseline QoL scores were comparable between groups. Post-intervention, the intervention group experienced significant improvements in QoL (p ≤ 0.05), while the control group showed a decline. OM severity was significantly reduced in the intervention group compared to the control group at both time points (p ≤ 0.05).
Educational guidelines are an effective intervention for reducing OM severity and improving QoL in oncology patients receiving chemotherapy. Implementation of these guidelines can enhance patient well-being and support optimal treatment outcomes.
摘要：
背景：口腔黏膜炎（OM）是化疗的常见副作用，对患者生活质量（QoL）有负面影响。教育指南可以提供减轻这些影响的策略。
目的：评估肿瘤化疗患者OM和QoL严重程度教育指南的有效性。
方法：进行准实验研究。患者（n=108）被随机分配到接受教育指南的干预组或接受常规护理的对照组。在基线和干预后1个月和3个月评估结果。数据是使用结构化访谈收集的，包括对个人特征的评估，临床资料,化疗副作用，OM严重性,和QoL。
结果：基线QoL评分在组间具有可比性。干预后，干预组QoL显著改善(p≤0.05)，而对照组则呈下降趋势。与对照组相比，干预组的OM严重程度在两个时间点均显着降低（p≤0.05）。
结论：教育指南是降低接受化疗的肿瘤患者OM严重程度和改善QoL的有效干预措施。实施这些指南可以增强患者的健康并支持最佳治疗结果。
目的：评估肿瘤化疗患者OM和QoL严重程度教育指南的有效性。
方法：进行准实验研究。患者（n=108）被随机分配到接受教育指南的干预组或接受常规护理的对照组。在基线和干预后1个月和3个月评估结果。数据是使用结构化访谈收集的，包括对个人特征的评估，临床资料,化疗副作用，OM严重性,和QoL。
结果：基线QoL评分在组间具有可比性。干预后，干预组QoL显著改善(p≤0.05)，而对照组则呈下降趋势。与对照组相比，干预组的OM严重程度在两个时间点均显着降低（p≤0.05）。
结论：教育指南是降低接受化疗的肿瘤患者OM严重程度和改善QoL的有效干预措施。实施这些指南可以增强患者的健康并支持最佳治疗结果。
