Abstract：
OBJECTIVE: Chronic cough, a common outpatient symptom, has various aetiologies, including upper airway cough syndrome, asthma, and gastroesophagoeal reflux. The potential link between dental issues and respiratory diseases has recently garnered attention. This study aims to investigate the association between masticatory difficulty and chronic cough using data from the 2011-2015 Korean National Health and Nutrition Examination Survey (KNHANES).
METHODS: Analysis included 9706 individuals from KNHANES. Participants self-reported masticatory function and chronic cough. Covariates included age, sex, underlying diseases, socioeconomic status, lifestyle factors, and laboratory markers. Binary logistic regression analysed odds ratios for chronic cough covariates. Multiple logistic regression assessed adjusted odds ratios for masticatory difficulty.
RESULTS: Masticatory difficulty prevalence was 32.2%, with chronic cough higher in this group (4.8%) than in the group without masticatory difficulty (3.0%). After adjusting for socioeconomic status, lifestyle factors, and laboratory markers, masticatory difficulty was significantly associated with greater chronic cough prevalence (odds ratio, 1.137; 95% confidence interval, 1.134-1.140).
CONCLUSIONS: Masticatory difficulty was linked with an elevated chronic cough risk in Korean healthy adults. Further research, including prospective studies and detailed investigations into gastroesophagoeal reflux disease and microbiological studies, is warranted to elucidate the impact of mastication on respiratory health. As masticatory difficulty may serve as a clinical indicator for chronic cough interdisciplinary collaboration between dental and respiratory health professionals can facilitate early intervention and enhance patient care.
METHODS: Analysis included 9706 individuals from KNHANES. Participants self-reported masticatory function and chronic cough. Covariates included age, sex, underlying diseases, socioeconomic status, lifestyle factors, and laboratory markers. Binary logistic regression analysed odds ratios for chronic cough covariates. Multiple logistic regression assessed adjusted odds ratios for masticatory difficulty.
RESULTS: Masticatory difficulty prevalence was 32.2%, with chronic cough higher in this group (4.8%) than in the group without masticatory difficulty (3.0%). After adjusting for socioeconomic status, lifestyle factors, and laboratory markers, masticatory difficulty was significantly associated with greater chronic cough prevalence (odds ratio, 1.137; 95% confidence interval, 1.134-1.140).
CONCLUSIONS: Masticatory difficulty was linked with an elevated chronic cough risk in Korean healthy adults. Further research, including prospective studies and detailed investigations into gastroesophagoeal reflux disease and microbiological studies, is warranted to elucidate the impact of mastication on respiratory health. As masticatory difficulty may serve as a clinical indicator for chronic cough interdisciplinary collaboration between dental and respiratory health professionals can facilitate early intervention and enhance patient care.
摘要：
目的：慢性咳嗽，一种常见的门诊症状，有各种病因，包括上呼吸道咳嗽综合征,哮喘,胃食管反流.牙科问题和呼吸系统疾病之间的潜在联系最近引起了人们的关注。本研究旨在使用2011-2015年韩国国家健康和营养检查调查（KNHANES）的数据调查咀嚼困难与慢性咳嗽之间的关系。
方法：分析包括来自KNHANES的9706名个体。参与者自我报告咀嚼功能和慢性咳嗽。协变量包括年龄，性别,潜在的疾病，社会经济地位,生活方式因素，和实验室标记。二元逻辑回归分析了慢性咳嗽协变量的比值比。多元逻辑回归评估咀嚼困难的调整后比值比。
结果：咀嚼困难患病率为32.2%，慢性咳嗽组(4.8%)高于无咀嚼困难组(3.0%)。在调整社会经济地位后，生活方式因素，和实验室标记，咀嚼困难与更高的慢性咳嗽患病率显著相关(优势比，1.137；95%置信区间，1.134-1.140)。
结论：在韩国健康成人中，咀嚼困难与慢性咳嗽风险升高有关。进一步研究,包括前瞻性研究和详细调查胃食管反流病和微生物学研究，有必要阐明咀嚼对呼吸健康的影响。由于咀嚼困难可以作为慢性咳嗽的临床指标，牙科和呼吸健康专业人员之间的跨学科合作可以促进早期干预并增强患者护理。
方法：分析包括来自KNHANES的9706名个体。参与者自我报告咀嚼功能和慢性咳嗽。协变量包括年龄，性别,潜在的疾病，社会经济地位,生活方式因素，和实验室标记。二元逻辑回归分析了慢性咳嗽协变量的比值比。多元逻辑回归评估咀嚼困难的调整后比值比。
结果：咀嚼困难患病率为32.2%，慢性咳嗽组(4.8%)高于无咀嚼困难组(3.0%)。在调整社会经济地位后，生活方式因素，和实验室标记，咀嚼困难与更高的慢性咳嗽患病率显著相关(优势比，1.137；95%置信区间，1.134-1.140)。
结论：在韩国健康成人中，咀嚼困难与慢性咳嗽风险升高有关。进一步研究,包括前瞻性研究和详细调查胃食管反流病和微生物学研究，有必要阐明咀嚼对呼吸健康的影响。由于咀嚼困难可以作为慢性咳嗽的临床指标，牙科和呼吸健康专业人员之间的跨学科合作可以促进早期干预并增强患者护理。
