PDF(Pubmed)
Abstract：
Intestinal failure manifests as an impaired capacity of the intestine to sufficiently absorb vital nutrients and electrolytes essential for growth and well-being in pediatric and adult populations. Although parenteral nutrition remains the mainstay therapeutic approach, the pursuit of a definitive and curative strategy, such as regenerative medicine, is imperative. Substantial advancements in the field of engineered intestinal tissues present a promising avenue for addressing intestinal failure; nevertheless, extensive research is still necessary for effective translation from experimental benchwork to clinical bedside applications.
摘要：
肠衰竭表现为肠道充分吸收儿科和成人人群中生长和健康所必需的重要营养素和电解质的能力受损。尽管肠外营养仍然是主要的治疗方法，追求明确和有效的策略，比如再生医学，势在必行。工程化肠组织领域的实质性进展为解决肠衰竭提供了有希望的途径；然而，从实验基准到临床床边应用的有效转化仍然需要广泛的研究。
