Abstract:
Metabolic bone diseases encompass a group of disorders characterized by abnormalities in bone metabolism, structure, or mineralization. These disorders negatively impact overall health and quality of life and place individuals at high risk for fracture, which may increase morbidity and mortality. Clinicians should understand who is at risk for these disorders, select individuals who warrant further workup, determine appropriate laboratory and imaging evaluation, interpret results in a clinical context, and choose an optimal management strategy based on the individual patient.
摘要:
代谢性骨疾病包括一组以骨代谢异常为特征的疾病,结构,或矿化。这些疾病会对整体健康和生活质量产生负面影响,并使个人面临骨折的高风险。这可能会增加发病率和死亡率。临床医生应该了解谁有这些疾病的风险,选择需要进一步检查的个人,确定适当的实验室和成像评估,在临床背景下解释结果,并根据患者个体选择最优的管理策略。