Abstract:
Men who have sex with men (MSM) are disproportionately impacted by sexually transmitted infections (STIs), including HIV and those preventable through vaccination such as mpox, HPV, HAV, and HBV. A retrospective cohort study was conducted to evaluate the effectiveness of counseling provided during mpox vaccination on the uptake of other recommended vaccines (HPV, HAV, and HBV) and to identify associated factors. Relevant covariates such as nationality, age, HIV status, and use of PrEP were retrieved from electronic medical records. Vaccination status data were retrieved from the regional vaccination registry. Of the 330 participants, 98.8% were males and the mean age was 40.6 years (SD: 11.2). Following consultation, a statistically significant increase for both HPV (from 25.8% to 39.1%) and HAV (from 26.7% to 36.1%) was observed (p < 0.001). The multivariate analysis showed a significant negative association between the uptake of HPV and HBV vaccines and foreign nationality (aOR 0.25 (95%CI 0.08-0.69), p = 0.012; and aOR 0.31 (95%CI 0.11-0.81), p = 0.021). The HBV vaccine uptake was negatively associated with increasing age. Our results suggest that tailored counseling can effectively bridge the gap in vaccine acceptance among vulnerable populations, thereby improving overall public health outcomes.
摘要:
男男性行为者(MSM)受到性传播感染(STIs)的影响不成比例。包括艾滋病毒和那些可以通过疫苗预防的,如水痘,HPV,HAV,和HBV。进行了一项回顾性队列研究,以评估在水痘疫苗接种期间提供的咨询对其他推荐疫苗(HPV,HAV,和HBV),并确定相关因素。相关协变量,如国籍,年龄,艾滋病毒状况,并从电子病历中检索PrEP的使用。从区域疫苗接种登记处检索疫苗接种状态数据。在330名参与者中,男性占98.8%,平均年龄为40.6岁(SD:11.2)。经过协商,观察到HPV(从25.8%到39.1%)和HAV(从26.7%到36.1%)的统计学显著增加(p<0.001).多变量分析显示,HPV和HBV疫苗的摄取与外国国籍之间存在显着负相关(aOR0.25(95CI0.08-0.69),p=0.012;和AOR0.31(95CI0.11-0.81),p=0.021)。HBV疫苗摄取与年龄增长呈负相关。我们的结果表明,量身定制的咨询可以有效地弥合脆弱人群在疫苗接受度方面的差距,从而改善整体公共卫生结果。